Perioperative Prophylaxe und Therapie von Infektionen – Perioperative Antibiotikaprophylaxe

Ina Tammer; Gernot Geginat; Dirk Schlüter

doi:10.1055/s-0031-1291946

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie, Inhaltsverzeichnis

Anästhesiol Intensivmed Notfallmed Schmerzther 2011; 46(10): 674-682
DOI: 10.1055/s-0031-1291946

Fachwissen

Anästhesie-Topthema: Perioperative Prophylaxe und Therapie von Infektionen

Perioperative Prophylaxe und Therapie von Infektionen – Perioperative Antibiotikaprophylaxe

Perioperative antimicrobial prophylaxis

Ina Tammer

,

Gernot Geginat

,

Dirk Schlüter

Abstract

Zusammenfassung

Die perioperative Antibiotikaprophylaxe (PAP) stellt eine wichtige, jedoch nicht die alleinige Maßnahme zur Prävention postoperativer Wundinfektionen dar. Ihre Wirksamkeit wurde in einer Vielzahl von Studien belegt und in nationalen und internationalen Leitlinien umgesetzt. Neben der Auswahl des Antibiotikums sind Art, Dauer und Zeitpunkt der Applikation wichtige Kriterien für den Erfolg der Prophylaxe. Der Artikel gibt einen Überblick über die zur PAP empfohlenen Antibiotika und deren Einfluss auf das normalerweise zu erwartende Erregerspektrum bei elektiven Eingriffen. Darüber hinaus werden die häufigsten Problemkeime postoperativer Wundinfektionen und der derzeitige Stellenwert alternativer Antibiotika diskutiert.

Abstract

Perioperative antimicrobial prophylaxis (AMP) is an important but not the only procedure to prevent surgical site infections. The effectiveness of AMP to prevent surgical site infections has been proven in numerous studies during the last decades and is part of national and international guidelines. The choice of the antibiotic as well as the duration, time point and mode of application strongly impact on the effectiveness of the prophylaxis. This article provides an overview on recommended antibiotics for AMP and their activity against the expected bacterial pathogens in elective surgery. Furthermore, the current spectrum of microorganisms most frequently isolated from surgical site infections and alternative antibiotic strategies are discussed.

Schlüsselwörter:

perioperative Antibiotikaprophylaxe - Prävention - postoperative Wundinfektion - MRSA

Key words:

perioperative antimicrobial prophylaxis - prevention - surgical site infections - MRSA

Volltext

Referenzen

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