Klin Monbl Augenheilkd 2012; 229(4): 437-438
DOI: 10.1055/s-0031-1299176
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© Georg Thieme Verlag KG Stuttgart · New York

Ocular involvement in idiopathic hypereosinophilic syndrome: a rare finding

Augenbeteiligung beim idiopathischen Hypereosinophilen Syndrom: ein seltener Befund
K. Balaskas
1   Jules-Gonin Eye Hospital, University of Lausanne, Switzerland
,
P. Wyss
2   Etablissements Hospitaliers du Nord Vaudois, Yverdon-les-Bains, Switzerland
,
Y. Guex-Crosier
1   Jules-Gonin Eye Hospital, University of Lausanne, Switzerland
› Author Affiliations
Further Information

Publication History

Publication Date:
11 April 2012 (online)

Background

Hypereosinophilic syndrome (HES) is a myeloproliferative disorder characterised by persistent eosinophilia associated with multiple organ damage. The three criteria required for the diagnosis of the disease are: a sustained absolute eosinophilic count in the serum greater than 1500/μl present for longer than 6 months, no aetiology for secondary eosinophilia present and identification of signs and symptoms of end-organ involvement [1] [2]. Despite significant progress in our understanding of the pathogenesis of some forms of hypereosinophilic syndrome, the current state of knowledge is still insufficient to formulate a new comprehensive etiologic definition of HES [3]. Very few reports can be retrieved describing ocular involvement in HES. Retinal arteriolar occlusions were observed in the pre-equatorial region and documented by angiography in one report [4], while the principal defects noted in a second report were occlusions of major retinal vessels, choroidal infarct, and patchy or delayed choroidal filling [5]. We present a case of extensive bilateral choroidal infiltrates in a patient suffering from idiopathic hypereosinophilia, potentially attributable to her disease.