Response to the Article: “Primary Aldosteronism: Are We Missing the Wood for the Trees?”

G. Piaditis; T. Pappa; A. Markou; A. Gouli; L. Papanastasiou; G. Kaltsas

doi:10.1055/s-0032-1316322

Hormone and Metabolic Research, Table of Contents

Horm Metab Res 2012; 44(12): 927-928
DOI: 10.1055/s-0032-1316322

Letter to the Editor

Response to the Article: “Primary Aldosteronism: Are We Missing the Wood for the Trees?”

Authors

G. Piaditis

¹Department of Endocrinology and Diabetes Center, “G. Gennimatas” General Hospital, Athens, Greece
T. Pappa

¹Department of Endocrinology and Diabetes Center, “G. Gennimatas” General Hospital, Athens, Greece
A. Markou

¹Department of Endocrinology and Diabetes Center, “G. Gennimatas” General Hospital, Athens, Greece
A. Gouli

¹Department of Endocrinology and Diabetes Center, “G. Gennimatas” General Hospital, Athens, Greece
L. Papanastasiou

¹Department of Endocrinology and Diabetes Center, “G. Gennimatas” General Hospital, Athens, Greece
G. Kaltsas

²Department of Pathophysiology, Laikon Hospital, Athens University School of Medicine, Athens, Greece

Abstract

This letter is a short response to Dr Funder’s recent commentary on primary aldosteronism under the title “Primary aldosteronism: are we missing the wood for the trees?”. We briefly discuss recent data from our department on autonomous aldosterone secretion (AAS) and the efficacy of mineralocorticoid receptor antagonists in a group of patients with AAS, that would otherwise remain undiagnosed.

Full Text

References

References
1 Funder JW. Primary aldosteronism: are we missing the wood for the trees?. Horm Metab Res 2012; 44: 251-253
2 Stowasser M, Sharman J, Leano R, Gordon RD, Ward G, Cowley D, Marwick TH. Evidence for abnormal left ventricular structure and function in normotensive individuals with familial hyperaldosteronism type I. J Clin Endocrinol Metab 2005; 90: 5070-5076
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5 Pappa T, Papanastasiou L, Kaltsas G, Markou A, Tsounas P, Androulakis I, Tsiavos V, Zografos G, Vamvakidis K, Samara C, Piaditis G. Pattern of adrenal hormonal secretion in patients with adrenal adenomas: the relevance of aldosterone in arterial hypertension. J Clin Endocrinol Metab 2012; 97: E537-E545
6 Piaditis GP, Kaltsas GA, Androulakis II, Gouli A, Makras P, Papadogias D, Dimitriou K, Ragkou D, Markou A, Vamvakidis K, Zografos G, Chrousos G. High prevalence of autonomous cortisol and aldosterone secretion from adrenal adenomas. Clin Endocrinol (Oxf) 2009; 71: 772-778
7 Markou A, Pappa T, Kaltsas G, Gouli A, Mitsakis K, Tsounas P, Prevoli A, Tsiavos V, Papanastasiou L, Zografos G, Chrousos G, Piaditis G. Evidence of autonomous aldosterone secretion in a cohort of normotensive individuals: a very high odds ratio for progression into arterial hypertension (under review).