Synlett 2013; 24(3): 276-280
DOI: 10.1055/s-0032-1317716
synpacts
© Georg Thieme Verlag Stuttgart · New York

An Update on Catalytic Strategies for the Synthesis of α-Hydroxyketones

Jan Streuff*
Institut für Organische Chemie und Biochemie, Albert-Ludwigs-Universität Freiburg, Albertstr. 21, 79104 Freiburg im Breisgau, Germany   Fax: +49(761)2038715   Email: jan.streuff@ocbc.uni-freiburg.de
› Author Affiliations
Further Information

Publication History

Received: 15 October 2012

Accepted after revision: 07 November 2012

Publication Date:
10 December 2012 (online)

Abstract

The catalytic asymmetric synthesis of α-oxygenated ketones is still a challenge to modern methodology. This SYNPACTS gives an overview on recent developments in this area and besides direct α-oxidation protocols, alternative strategies that make use of redox-neutral or reductive conditions are discussed.

 
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