Neuropediatrics 2013; 44(03): 159-162
DOI: 10.1055/s-0032-1327773
Short Communication
Georg Thieme Verlag KG Stuttgart · New York

Systemic Effects of Hypothermia due to Hypothalamic Dysfunction after Resection of a Craniopharyngioma: Case Report and Review of Literature

L. de Vetten
1   Beatrix Children's Hospital, Department of Pediatrics, University Medical Centre Groningen, Groningen, The Netherlands
,
G. Bocca
1   Beatrix Children's Hospital, Department of Pediatrics, University Medical Centre Groningen, Groningen, The Netherlands
› Author Affiliations
Further Information

Publication History

09 April 2012

21 August 2012

Publication Date:
09 October 2012 (online)

Abstract

Objective With this case report, we aim to improve recognition of the systemic effects of hypothermia due to hypothalamic dysfunctioning. We present a patient who developed temperature dysregulation after surgery for craniopharyngioma. He suffered from several episodes of hypothermia associated with a decreased level of consciousness, hypoventilation, bradycardia, pancreatitis, and pancytopenia. Rewarming resulted in complete recovery of all symptoms.

Data Sources We discuss the literature on the pathophysiological consequences of hypothermia, referring to several medical databases (Cochrane, SUMSearch, Trip database, and PubMed).

Conclusion Hypothermia due to hypothalamic dysfunction can result in several systemic complications with complete recovery of all symptoms by rewarming.

 
  • References

  • 1 Caldarelli M, Massimi L, Tamburrini G, Cappa M, Di Rocco C. Long-term results of the surgical treatment of craniopharyngioma: the experience at the Policlinico Gemelli, Catholic University, Rome. Childs Nerv Syst 2005; 21 (8–9) 747-757
  • 2 Collins AM, Danzl DF. Hypothermia with profound anemia and pancreatitis. Wilderness Environ Med 2006; 17 (1) 31-35
  • 3 Kopterides P, Synetos A, Theodorakopoulou M, Armaganidis A, Lerakis S. Osborn waves in sepsis-induced hypothermia. Int J Cardiol 2008; 129 (2) 297-299
  • 4 Strohmer B, Pichler M. Atrial fibrillation and prominent J (Osborn) waves in critical hypothermia. Int J Cardiol 2004; 96 (2) 291-293
  • 5 Hauer JM. Central hypothermia as a cause of acute pancreatitis in children with neurodevelopmental impairment. Dev Med Child Neurol 2008; 50 (1) 68-70
  • 6 Griffiths AP, Henderson M, Penn ND, Tindall H. Haematological, neurological and psychiatric complications of chronic hypothermia following surgery for craniopharyngioma. Postgrad Med J 1988; 64 (754) 617-620
  • 7 Lo L, Singer ST, Vichinsky E. Pancytopenia induced by hypothermia. J Pediatr Hematol Oncol 2002; 24 (8) 681-684
  • 8 Polderman KH, Girbes ARJ. Severe electrolyte disorders following cardiac surgery: a prospective controlled observational study. Crit Care 2004; 8 (6) R459-R466
  • 9 Arciniegas DB, Held K, Wagner P. Cognitive impairment following traumatic brain injury. Curr Treat Options Neurol 2002; 4 (1) 43-57
  • 10 Zavadenko NN, Guzilova LS. Sequelae of closed craniocerebral trauma and the efficacy of piracetam in its treatment in adolescents. Neurosci Behav Physiol 2009; 39 (4) 323-328
  • 11 Flicker L, Grimley Evans G. Piracetam for dementia or cognitive impairment. Cochrane Database Syst Rev 2001; (2) CD001011
  • 12 Greenberg RA, Rittichier KK. Pediatric nonenvironmental hypothermia presenting to the emergency department: Episodic spontaneous hypothermia with hyperhidrosis. Pediatr Emerg Care 2003; 19 (1) 32-34