Solitary Breast Cancer Metastasis to the Esophagus – a Multimodal Diagnostic Approach

R. Talanow; H. Vieweg; R. Andresen

doi:10.1055/s-0033-1335262

Zeitschrift für Gastroenterologie, Table of Contents

Z Gastroenterol 2013; 51(7): 635-637
DOI: 10.1055/s-0033-1335262

Kasuistik

Solitary Breast Cancer Metastasis to the Esophagus – a Multimodal Diagnostic Approach

Seltene Beobachtung einer solitären Brustkrebsmetastase im Ösophagus – ein multimodaler diagnostischer Ansatz

Authors

R. Talanow

¹Radiology, EduRad, Lincoln, CA, USA
H. Vieweg

²Institute of Diagnostic and Interventional Radiology / Neuroradiology, Westküstenklinikum Heide, Academic Teaching Hospital of the Universities of Kiel, Luebeck and Hamburg
R. Andresen

²Institute of Diagnostic and Interventional Radiology / Neuroradiology, Westküstenklinikum Heide, Academic Teaching Hospital of the Universities of Kiel, Luebeck and Hamburg

Abstract

We present a case of late breast cancer metastasis over 15 years since the initial diagnosis which was highly unusual because of its solitary aspect with no other evidence of the disease and its uncommon localization in the esophagus. With a history of breast cancer, several differential diagnoses for suspicious space-occupying masses need to be considered, like radiation-induced cancer or multiple neoplasm. A multimodal diagnostic approach can lead to the correct diagnosis. Endoscopy, endoscopic ultrasound (EUS) including EUS-guided fine-needle aspiration (FNA), CT and PET/CT findings are provided.

Zusammenfassung

Wir präsentieren den ungewöhnlichen Fall einer spät aufgetretenen Brustkrebsmetastase, welche 15 Jahre nach der Erstdiagnose als solitäre Manifestation im Ösophagus entdeckt wurde. Mit Brustkrebs in der Vorgeschichte sind diverse Differenzialdiagnosen für unklare ösophageale Raumforderungen zu beachten, wie strahleninduzierte Tumoren und multiple Neoplasien. Eine multimodale diagnostische Herangehensweise ist zur Diagnosestellung zielführend. In diesem Zusammenhang werden die Ergebnisse von Endoskopie, Endosonographie, endosonographischer Feinnadelaspiration, CT und PET/CT vorgestellt.

Key words

breast cancer - esophageal metastasis - PET/CT

Schlüsselwörter

Brustkrebs - Ösophagusmetastase - PET/CT

Full Text

References

References
1 Mizobuchi S, Tachimori Y, Kato H et al. Metastatic esophageal tumors from distant primary lesions: report of three esophagectomies and study of 1835 autopsy cases. Jpn J Clin Oncol 1997; 27: 410-414
2 Lottini M, Neri A, Vuolo G et al. Duodenal obstruction from isolated breast cancer metastasis: a case report. Tumori 2002; 88: 427-429
3 Raissouni S, Raissouni F, Rais G et al. Radiation induced esophageal adenocarcinoma in a woman previously treated for breast cancer and renal cell carcinoma. BMC Res Notes 2012; 5: 426
4 Singh A, Khare IC, Dixit AK et al. Successfully treated synchronous double malignancy of the breast and esophagus: a case report. J Med Case Rep 2010; 4: 169
5 Ahsan H, Neugut Al, Gammon MD. Association of adenocarcinoma and squamous cell carcinoma of the esophagus with tobacco-related and other malignancies. Cancer Epidemiol Biomarkers Prev 1997; 6: 779-782
6 Sato Y, Horiguchi H, Yoshida M et al. Four cases of esophageal metastasis from breast cancer. Nihon Shokakibyo Gakkai Zasshi 2012; 109: 921-928
7 Simchuk EJ, Low DE. Direct esophageal metastasis from a distant primary tumor is a submucosal process: a review of six cases. Dis Esophagus 2001; 14: 247-250
8 Erman M, Karaoğlu A, Oksüzoğlu B et al. Solitary esophageal metastasis of breast cancer after 11 years: a case report. Med Oncol 2002; 19: 171-175
9 Kovács O, Kotsis L, Krasznai G. Solitary oesophageal metastasis of breast cancer after 17 years latency. MagySeb 2007; 60: 307-309
10 Sunada F, Yamamoto H, Kita H et al. A case of esophageal stricture due to metastatic breast cancer diagnosed by endoscopic mucosal resection. Jpn J Clin Oncol 2005; 35: 483-486
11 Koike M, Akiyama S, Kodera Y et al. Breast carcinoma metastasis to the esophagus: report of two cases. Hepatogastroenterology 2005; 52: 1116-1118