Synlett 2014; 25(14): 1941-1945
DOI: 10.1055/s-0033-1338645
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© Georg Thieme Verlag Stuttgart · New York

Recent Progress in the Synthesis of Functionalized β-Lactams through Transition-Metal-Catalyzed C(sp3)–H Amidation

Qi Zhang
Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. of China, Fax: +86(571)87951895   Email: bfshi@zju.edu.cn
,
Kai Chen
Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. of China, Fax: +86(571)87951895   Email: bfshi@zju.edu.cn
,
Bing-Feng Shi*
Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. of China, Fax: +86(571)87951895   Email: bfshi@zju.edu.cn
› Author Affiliations
Further Information

Publication History

Received: 22 March 2014

Accepted after Revision: 14 April 2014

Publication Date:
28 May 2014 (online)

Dedicate to Professor Li-Xin Dai on the occasion of his 90th birthday

Abstract

Transition-metal-catalyzed C–H activation and C–N bond formation has become one of the most important methods to generate heterocycles. Herein, recent progress in the synthesis of functionalized β-lactams through Pd- and Cu-catalyzed intramolecular C(sp3)–H amidation is highlighted.

 
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