Solvent- and Ligand-Free Palladium-Catalyzed Amination of Aryl Halides

Luca Basolo; Alice Bernasconi; Gianluigi Broggini; Silvia Gazzola; Egle M. Beccalli

doi:10.1055/s-0033-1339659

Synthesis, Inhaltsverzeichnis

Synthesis 2013; 45(22): 3151-3156
DOI: 10.1055/s-0033-1339659

paper

Solvent- and Ligand-Free Palladium-Catalyzed Amination of Aryl Halides

Autoren

Luca Basolo

^aDISFARM, Sezione di Chimica Generale e Organica ‘A. Marchesini’ Università degli Studi di Milano, via Venezian 21, 20133 Milano, Italy Fax: +39(02)50314476 eMail: egle.beccalli@unimi.it
Alice Bernasconi

^aDISFARM, Sezione di Chimica Generale e Organica ‘A. Marchesini’ Università degli Studi di Milano, via Venezian 21, 20133 Milano, Italy Fax: +39(02)50314476 eMail: egle.beccalli@unimi.it
Gianluigi Broggini

^bDipartimento di Scienza e Alta Tecnologia, Università dell’Insubria, via Valleggio 11, 22100 Como, Italy eMail: gianluigi.broggini@uninsubria.it
Silvia Gazzola

^bDipartimento di Scienza e Alta Tecnologia, Università dell’Insubria, via Valleggio 11, 22100 Como, Italy eMail: gianluigi.broggini@uninsubria.it
Egle M. Beccalli*

^aDISFARM, Sezione di Chimica Generale e Organica ‘A. Marchesini’ Università degli Studi di Milano, via Venezian 21, 20133 Milano, Italy Fax: +39(02)50314476 eMail: egle.beccalli@unimi.it

Abstract

Alle Artikel dieser Rubrik

Abstract

An environmentally friendly and economically favorable approach to the formation of C–N bonds is presented. The methodology is particularly interesting in that the reaction is realized under both solvent- and ligand-free conditions and involves the use of a low loading of a palladium catalyst dispersed with the reactants on a suitable solid support. The reaction proceeds rapidly under microwave irradiation.

Key words

arylation - amination - catalysis - solid-phase synthesis - green-chemistry - microwave

Volltext

Referenzen

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