Pädiatrie up2date 2013; 08(04): 371-387
DOI: 10.1055/s-0033-1344506
Neuropädiatrie/Psychiatrie
© Georg Thieme Verlag KG Stuttgart · New York

Chronische Müdigkeit

Marianne Caflisch
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
25. November 2013 (online)

Fazit

Chronische Müdigkeit ist unter Jugendlichen häufig. Noch allzu oft wird als Ursache eine ungesunde Lebensweise, Motivationsverlust, übermäßiger Medienkonsum oder ungenügender Schlaf angenommen. Immer häufiger zeigen Studien, dass bei anhaltender Müdigkeit im Jugendalter auch an die Diagnose eines Chronischen Erschöpfungssyndroms gedacht werden muss. Dabei handelt es sich um eine Ausschlussdiagnose, da bis anhin keine diagnostischen Labortests oder Marker existieren. Ein sorgfältiges Diagnoseverfahren soll möglichst rasch Klärung bringen, um Komplikationen wie Schulabsentismus, körperliche Inaktivität und soziale Isolation zu verhindern. Zudem sollten Behandlungsansätze immer multifokal angelegt werden.

Mangels Objektivität ist die Diagnose „Chronisches Erschöpfungssyndrom“ noch heute voller Kontroversen.

 
  • Literatur

  • 1 Delgrande Jordan M, Windlin B. Die Studie „Health behaviour in schoolaged children“ (HBSC) in der Schweiz − Ziele, Methoden und ausgewählte Ergebnisse. Paediatrica 2012; 23: 29-30
  • 2 Gluckman SJ. Clinical features and diagnosis of chronic fatigue syndrome. Wolters Kluwer Health: UpToDate. 21. 9. 2012 Im Internet: http://www.uptodate.com/contents/clinical-features-and-diagnosis-of-chronic-fatigue-syndrome (Stand: 30. 6. 2013)
  • 3 Centers for Disease Control and Prevention. Chronic Fatigue Syndrome (CFS). 14. 5. 2012 Im Internet: http://www.cdc.gov/cfs/general (Stand: 30. 6. 2013)
  • 4 Beverley DW. Chronic fatigue syndrome in children. Current Paediatrics 2005; 15: 246-252
  • 5 Ter Wolbeek M, van Doornen LJ et al. Severe fatigue in adolescents: a common phenomenon?. Pediatrics 2006; 117: e1078-1086
  • 6 Rimes KA, Goodman R, Hotopf M et al. Incidence, prognosis and risk factors for fatigue and chronic fatigue syndrome in adolescents: a prospective community study. Pediatrics 2007; 119: e603-609
  • 7 Nijhof SI, Maijer K, Bleijenberg C et al. Adolescent chronic fatigue syndrome: Prevalence, indicence and morbidity. Pediatrics 2011; 127: e1169-1175
  • 8 Chalder T, Goodman R, Wessely S et al. Epidemiology of chronic fatigue syndrome and self-reported myalgic encephalomyelitis in 5−15 year olds: cross sectional study. BMJ 2003; 327: 654-655
  • 9 Wessely S, Chalder T, Hirsch S et al. The prevalence and morbidity of chronic fatigue and chronic fatigue syndrome: a prospective primary care study. Am J Public Health 1997; 87: 1449-1455
  • 10 Haines LC, Saidi G, Cooke RWI. Prevalence of severe fatigue in primary care. Arch Dis Child 2005; 90: 367-368
  • 11 Mayo Clinic Staff. Chronic fatigue syndrome: Risk factors. 18. 6. 2011 Im Internet: http://www.mayoclinic.com/health/chronic-fatigue-syndrome/DS00395 (Stand: 30. 6. 2013)
  • 12 Kennedy G, Underwood C, Belch JJ. Physical and functional impact of chronic fatigue syndrome/myalgic encephalomyelitis in childhood. Pediatrics 2010; 125: e1324-1330
  • 13 Cavanaugh Jr RM. Evaluating adolescents with fatigue: Ever get tired of it?. Pediatr Rev 2002; 23: 337
  • 14 Katz BZ, Shiraishi Y, Mears CJ et al. Chronic fatigue syndrome after infectious mononucleosis in adolescents. J Pediatr 2010; 157: 468-472
  • 15 Klutts S, Ford BA et al. Evidence-Based Approach for Interpretation of Epstein-Barr Virus Serological Patterns. J Clin Microbiol 2009; 47: 3204-3210
  • 16 Wyller VB, Helland IB. Relationship between autonomic cardiovascular control, case definition, clinical symptoms and functional disability in adolescent chronic fatigue syndrome: an exploratory study. Biopsychosoc Med 2013; 7: 5
  • 17 Jones JF, Nicholson A, Nisenbaum R et al. Orthostatic instability in a population-based study of chronic fatigue syndrome. Am J Med 2005; 118: 1415
  • 18 Sulheim D, Hurum H, Helland IB et al. Adolescent chronic fatigue syndrome; a follow-up study displays concurrent improvement of circulatory abnormalities and clinical symptoms. Biopsychosoc Med 2012; 6: 10 DOI: DOI: 10.1186/1751-0759-6-10.
  • 19 Mathias CJ, Low DA, Iodice V et al. Postural tachycardia syndrome – current experience and concepts (Review). Nat Rev Neurol 2012; 8: 22-34
  • 20 Verdon F, Burnand B, Stubi CL et al. Iron supplementation for unexplained faituge in non-anaemic women: double blind randomized placebo controlled trial. BMJ 2003; 326: 1-4
  • 21 Antiel RM, Caudill JS, Burkhardt BE et al. Iron insufficiency and hypovitaminosis D in adolscents with chronic fatigue and orthostatic intolerance. South Med J 2011; 104: 609-611
  • 22 Vaucher P, Druais PL et al. Effect of iron supplementation on fatigue in nonanemic menstruating women with low ferritin: a randomized controlled trial. CMAJ 2012; 184: 1247-1254
  • 23 Jenni OG, Iglowstein J, Benz C, Largo R. Perzentilenkurven für die Schlafdauer in den ersten 16 Lebensjahren. Pädiatrische Praxis 2003; 63: 481-489
  • 24 Datta AN, Trachsel D, Roth B. Chronische Tagesschläfrigkeit im Jugendalter. In: Pädiatrie. 5. Neuhausen a/Rhf. (CH): Rosenfluh; 2011: 25−28 Im Internet: http://rosenfluh.ch/rosenfluh/articles/download/2841/08_Tagesschlaf_5.11.pdf
  • 25 Ter Wolbeek M, van Doornen LJP, Kavelaars A et al. Fatigue, depressive symptoms, and anxiety from adolescence up to young adulthood: A longitudinal study. Brain Behav Immun 2011; 25: 1249-1255
  • 26 Bould H, Lewis G, Emond A et al. Depression and anxiety in children with CFS/ME: cause or effect?. Arch Dis Child 2011; 96: 211-214
  • 27 Roberts RE, Duong HT. Depression and insomnia among adolescents: a prospective perspective. J Affect Disord 2013; 148: 66-71
  • 28 Prager LM. Depression and suicide in children and adolescents. Pediatr Rev 2009; 30: 199-206
  • 29 Eglinton R, Chung MC. The relationship between posttraumatic stress disorder, illness cognitions, defence styles, fatigue severity and psychological well-being in chronic fatigue syndrome. Psychiatry Res 2011; 188: 245-252
  • 30 Goldenring DM, Rosen D. Getting into Adolescent Heads. Un essential update. Contemporary Pediatrics 2004; 21: 64-90
  • 31 Nater UM, Maloney E et al. Cumulative life stress in chronic fatigue syndrome. Psychiatry Res 2011; 189: 318-320
  • 32 Bell DS. Treating Pediatric CFS. Charlotte, USA: CFIDS Association of America; 2000 Herbst Im Internet: http://cfids.org/archives/2000rr/2000-rr4-article01.asp (Stand 30. 6. 2013)
  • 33 Fisher H, Crawley E. Why do young people with CFS/ME feel anxious? A qualitative study. Clin Child Psychol Psychiatry 2012; DOI: DOI: 10.1177/1359104512460862.
  • 34 Bell DS, Jordan K, Robinson M. Thirteen-year folllow-up of children and adolescents with chronic fatigue syndrome. Pediatrics 2001; 107: 994-998
  • 35 Sankey A, Hill CM, Brown J et al. A follow-up study of chronic fatigue syndrome in children and adolescents: Symptom and school absenteeism. Clin Child Psychol Psychiatry 2006; 11: 126-138
  • 36 Van de Putte EM, van Doornen LJ, Engelbert RH et al. Mirrored symptoms in mother and child with chronic fatigue syndrome. Pediatrics 2006; 117: 2074-2079
  • 37 Crawley E, Hughes R, Northstone K et al. Chronic disabling fatigue at age 13 and association with family adversity. Pediatrics 2012; 130: e71-79
  • 38 Knoop H, Stulemeijer M, de Jong LW et al. Efficacy of cognitive behavioural therapy for adolescents with chronic fatigue syndrome: long-term follow-up of a randomized, controlled trial. Pediatrics 2008; 121: e619-625
  • 39 Anbu AT, Cleary AG. Chronic fatigue syndrome/myalgic encephalopathy in children. Paediat Child Health 2009; 19: 84-89
  • 40 Kuo DZ, Cheng TL, Rowe PC. Successful use of a primary care practice – speciality collaboration in the care of an adolescent with chronic fatigue syndrome. Pediatrics 2007; 120: e1536-1539
  • 41 National Institute for Health and Clinical Excellence. Chronic fatigue syndrome/myalgic encephalomyelitis (or encephalopathy); diagnosis and management. Clinical guidelines, CG53. (August 2007) Im Internet: http://guidance.nice.org.uk/CG53 (Stand 30. 6. 2013)
  • 42 Touitou Y. Adolescent sleep mislaignment and chronic jet lag: A matter of public health. J Physiol Paris 2013; DOI: DOI: 10.1016/j.jphysparis.2013.03.008.
  • 43 Cain N, Gradisar M. Electronic media use and sleep in school-aged children and adolescents: A review. Sleep Med 2010; 11: 735-742
  • 44 Browne T, Chalder T. Chronic fatigue syndrome. Psychiatry 2009; 8: 153-157
  • 45 Wilson L, Whitehead L, Burell B. Learning to live well with chronic fatigue; the personal perspective. J Adv Nurs 2011; 67: 2161-2169