Int J Sports Med 2014; 35(06): 511-516
DOI: 10.1055/s-0033-1354358
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© Georg Thieme Verlag KG Stuttgart · New York

Effects of Whole Body Vibration Plus Diet on Insulin-Resistance in Middle-Aged Obese Subjects

A. Bellia
1  Department of Systems Medicine, University of Rome “Tor Vergata“, Rome, Italy
,
M. Sallì
2  Department of Clinical Sciences and Translational Medicine, University of Rome “Tor Vergata“, Rome, Italy
,
M. Lombardo
1  Department of Systems Medicine, University of Rome “Tor Vergata“, Rome, Italy
,
M. D’Adamo
1  Department of Systems Medicine, University of Rome “Tor Vergata“, Rome, Italy
,
V. Guglielmi
1  Department of Systems Medicine, University of Rome “Tor Vergata“, Rome, Italy
,
C. Tirabasso
1  Department of Systems Medicine, University of Rome “Tor Vergata“, Rome, Italy
,
L. Giordani
2  Department of Clinical Sciences and Translational Medicine, University of Rome “Tor Vergata“, Rome, Italy
,
M. Federici
1  Department of Systems Medicine, University of Rome “Tor Vergata“, Rome, Italy
,
D. Lauro
1  Department of Systems Medicine, University of Rome “Tor Vergata“, Rome, Italy
,
C. Foti
2  Department of Clinical Sciences and Translational Medicine, University of Rome “Tor Vergata“, Rome, Italy
,
P. Sbraccia
1  Department of Systems Medicine, University of Rome “Tor Vergata“, Rome, Italy
› Author Affiliations
Further Information

Publication History



accepted after revision 26 July 2013

Publication Date:
13 November 2013 (online)

Abstract

We investigated the early effects of whole body vibration (WBV) added to hypocaloric diet on insulin-resistance and other parameters associated with glucose regulation in sedentary obese individuals. We randomly assigned 34 patients to WBV plus hypocaloric diet (WBV group) or diet alone (CON group) for 8 weeks. Fasting and post-load glucose, insulin, lipids, C-reactive protein, tumor necrosis factor-α, leptin, adiponectin were assessed. Insulin sensitivity index (ISI) was derived from oral-glucose-tolerance test. Body composition was evaluated with dual-energy X-ray absorptiometry. Both groups lost approximately 5% of weight, with greater reduction of body fat in WBV than in CON (−7.1±1.2 Kg vs. −5.3±1.0 Kg, p=0.003). Percent variation of ISI was more pronounced in WBV than in CON group (+35±4% vs. + 22±5%, p=0.002), accompanied by slight improvement in post-load glucose (−1.07±0.02 vs. − 0.12±0.01 mmol/l, p=0.031) but without changes in fasting levels. Adiponectin significantly increased in WBV group compared with CON (p=0.021 for comparison) whereas no differences in leptin and inflammatory markers were observed. In middle-aged sedentary obese subjects, WBV added to hypocaloric diet for 8 weeks improved body composition, insulin-resistance, glucose regulation and adiponectin levels to a greater extent compared with diet alone. Efficacy and feasibility of this approach in the long term need to be ascertained.