Controlled ovarian hyperstimulation and artificial reproduction with following intrauterine gravity after bilateral serous ovarian borderline tumour – Case report

Ovarian borderline tumours – treated surgically – are associated with a favourable overall survival (OAS). Incomplete surgical removal for fertility preservation may result in a higher recurrence rate and lower OAS. Nevertheless performing controlled ovarian hyperstimulation (COH) after surgery may result in a soon onset of pregnancy.

We report a case of bilateral serous ovarian borderline tumor in a young woman with the desire for children.

Case report: A 33-year-old woman with the desire to have children presented to our department with a history of bilateral ovarian borderline tumors, oophorectomy one sided and partial oophorectomy on the other side.

When the patient presented to our department, several cystic ovarian lesions were detected and removed laparoscopically. Histology was benign. One cycle of COH and artificial reproduction (ART) was performed, but no pregnancy was achieved after transfer of two embryos. Afterwards sonography showed ovarian cysts again. After discussion of the patient's medical history, the benign histology of the last laparoscopy and the normal levels of tumor marker, the couple wished to perform another cycle of COH and ART, which resulted in an ongoing pregnancy after transfer of two embryos.

Discussion: Ovarian borderline tumors in fertile women may be treated with fertility preserving surgery, especially if the disease is limited to the ovaries. COH with ART may be performed after surgery to achieve a pregnancy. As soon as family planning is finished, surgical completion should be performed. Long term studies are needed to report the survival rates of women with similar medical histories.