Slovenia is a highly endemic region for Lyme borreliosis. We present three patients
with multiple erythema migrans and simultaneous isolation of Borrelia burgdorferi sensu lato from blood and cerebrospinal fluid. The patients were identified in a
prospective study on children with multiple erythema migrans in whom central nervous
system involvement was actively searched. The patients had no obvious symptoms and
signs of central nervous system involvement. At the end of 14-day treatment with ceftriaxone
the patients were free of signs and symptoms of borrelial infection. We stressed the
importance of cerebrospinal fluid investigations and early appropriate antibiotic
treatment in these patients.
Keywords
Lyme borreliosis - borrelia burgdorferi sensu lato - multiple erythema migrans - pathogenesis
- treatment
