Synthesis, Inhaltsverzeichnis Synthesis 2016; 48(21): 3701-3712DOI: 10.1055/s-0035-1562435 paper © Georg Thieme Verlag Stuttgart · New YorkEasy Synthesis of Two Positional Isomeric Tetrazole Libraries Authors Yuanze Wang Pravin Patil Alexander Dömling* Artikel empfehlen Abstract Artikel einzeln kaufen(opens in new window) Alle Artikel dieser Rubrik(opens in new window) Abstract A fast and efficient synthesis of libraries of positional isomeric 1H-tetrazoles and 5H-tetrazoles, for the purpose of testing binding hypothesis of isomeric tetrazoles in fragment-based drug discovery, is described. Key words Key words1H-tetrazole - 5H-tetrazole - cyanoacetamide - isocyanoacetamide - [2+3] cycloaddition - Oliveri-Mandala and Alagna reaction - fragment-based drug discovery Volltext Referenzen References 1 These authors contributed equally to this article. 2 Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE. Nucleic Acids Res. 2000; 28: 235 3a Herr RJ. Bioorg. Med. Chem. 2002; 23: 2699 3b Matta CF, Arabi AA, Weaver DF. Eur. J. Med. Chem. 2010; 45: 1868 4 Murray CW, Rees DC. Angew. Chem. Int. Ed. 2016; 55: 488 5 Hoekstra WJ, Hargrove TY, Wawrzak Z, da Gama Jaen Batista D, da Silva Cristiane F, Nefertiti AS. G, Rachakonda G, Schotzinger RJ, Villalta F, Soeiro MC, Lepesheva GI. Antimicrob. Agents Chemother. 2016; 60: 1058 6 Chen Y, Shoichet BK. Nat. Chem. Biol. 2009; 5: 158 7a Wang K, Nguyen K, Huang Y, Dömling A. ACS. Comb. Sci. 2009; 11: 920 7b Dömling A, Beck B, Fuchs T, Yazbak A. ACS Comb. Sci. 2006; 8: 872 8 Finnegan WG, Henry RA, Lofquist R. J. Am. Chem. Soc. 1958; 80: 3908 9a Mani P, Singh AK, Awasthi SK. Tetrahedron Lett. 2014; 55: 1879 9b Gawande SD, Raihan MJ, Zanwar M, Kavala V, Janreddy D, Kuo CW, Chen ML, Kuo TS, Yao CF. Tetrahedron 2013; 69: 1841 9c Gawande SD, Raihan MJ, Zanwar MR, Kavala V, Janreddy D, Kuo CW, Chen ML, Kuo TS, Yao CF. Tetrahedron 2013; 69: 1841 9d Das B, Reddy CR, Kumar DN, Krishnaiah M, Narender R. Synlett 2010; 391 9e Yoneyama H, Usami Y, Komeda S, Harusawa S. Synthesis 2013; 45: 1051 9f Roh J, Artamonova TV, Vávrová K, Koldobskii GI, Hrabálek A. Synthesis 2009; 2175 9g Vorona S, Artamonova T, Zevatskii Y, Myznikov L. Synthesis 2014; 46: 781 9h Cantillo D, Gutmann B, Kappe CO. J. Am. Chem. Soc. 2011; 133: 4465 10 Kappe CO, Stadler A, Dallinger D. Microwaves in Organic and Medicinal Chemistry . In Methods and Principles in Medicinal Chemistry . Vol. 52. Mannhold R, Kubinyi H, Folkers G. Wiley-VCH; Weinheim: 2012: 487 11 Oliveri-Mandala E, Alagna B. Gazz. Chim. Ital. 1910; 40 (II): 441 Zusatzmaterial Zusatzmaterial Supporting Information (PDF)
