Facial plast Surg 2015; 31(04): 386-395
DOI: 10.1055/s-0035-1563694
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Current Strategies in the Treatment of Scars and Keloids

Markus V. Heppt1, Helmut Breuninger2, Markus Reinholz1, Gabriele Feller-Heppt3, Thomas Ruzicka1, Gerd G. Gauglitz1
  • 1Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich, Germany
  • 2Department of Dermatology, Eberhard-Karls University Tübingen, Tübingen, Germany
  • 3Skin and Face Clinic, Baden-Baden, Germany
Further Information

Publication History

Publication Date:
15 September 2015 (online)


Hypertrophic scars (HTSs) and keloids are a major health concern for aesthetic and functional reasons. Despite a plethora of rapidly evolving treatment options and technical advances, the management of pathologic scarring remains difficult. The development of standardized treatment algorithms has been problematic for years due to the lack of sound randomized controlled trials. Expert panels are more and more establishing guidelines to provide an evidence-based framework on a national and international level. This article aims to evaluate the current strategies and upcoming trends in the therapy and prevention of unpleasant scars and keloids from a clinical perspective. There is strong evidence to support a growing role of early combination treatments, particularly the application of 5-fluoruracil adjunct to intralesional steroid injections. Furthermore, the use of fractional ablative laser technologies such as the CO2 laser has recently yielded promising results with respect to aesthetic outcomes and patient satisfaction at tolerable side effects.