Semin intervent Radiol 2015; 32(04): 349-355
DOI: 10.1055/s-0035-1564706
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Irreversible Electroporation

Govindarajan Narayanan
1  Division of Vascular and Interventional Radiology, Department of Radiology, University of Miami-Miller School of Medicine, Miami, Florida
› Author Affiliations
Further Information

Publication History

Publication Date:
10 November 2015 (online)


Irreversible electroporation (IRE) is a predominantly nonthermal ablative technology that uses high-voltage, low-energy DC current pulses to induce cell death. Thermal ablative technologies such as radiofrequency ablation, microwave ablation, and cryoablation have several applications in oncology but have limitations that have been established. IRE has shown promise to overcome some of these limitations. This article reviews the basics of the technology, patient selection, clinical applications, practical pointers, and the published data.