Abstract
This article provides an overview of perineural spread of head and neck malignancy.
It defines the problem and explores some of the unique features, which occur with
this pathology. The expectation is for a better understanding of this extraordinary
disease, hopefully leading to earlier diagnosis and for a more consistent reporting
of results. It summarizes the topics to be covered in this special edition, which
should leave the reader with a fairly complete understanding of the contemporary issues
of perineural spread.
Keywords
perineural invasion - perineural spread - head and neck - skin cancer - squamous cell
carcinoma - adenoid cystic carcinoma - skull base surgery