Facial plast Surg 2016; 32(02): 225-231
DOI: 10.1055/s-0036-1579782
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O2C Laser Doppler and Digital Photo Analysis for Treatment Evaluation of Beta-Glucan versus Provitamin Pantothenic Acid of Facial Burns

Daniel Thieme1, Gerald Spilker1, Rolf Lefering2, Christian Weinand1, 3
  • 1Department of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, University Hospital Cologne-Merheim, Burns, Cologne, Germany
  • 2The Institute for Research in Operative Medicine (IFOM), Universitat Witten/Herdecke, Cologne, Germany
  • 3Department of General Surgery, The Washington Hospital Center, Washington, District of Columbia
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Publication History

Publication Date:
20 April 2016 (online)


Various creams are available for superficial second-degree burns (SSDB) of the face. We evaluated provitamin pantothenic acid versus β-glucan for SSDB of the face using the O2C laser Doppler system and digital photo analysis. Out of 20 patients (January to December 2012) with facial burns, 7 with SSDB of both cheeks were included to our study. Burned cheek wounds were treated using pantothenic acid or β-glucan. Digital photos of marked regions were taken daily from predefined distances. Microcirculation was measured at marked regions for 7 days at scheduled time points using the O2C laser Doppler. Data were evaluated using the SPSS program (SPSS Inc., Chicago, IL). Wounds treated with β-glucan showed faster reepithelialization. O2C laser Doppler measurements showed faster increase in SO2, microvascular perfusion, hemoglobin content, and blood flow. This correlated good with clinical Vancouver Scar Scale results. Although not statistically significant, β-glucan cream therapy of SSDB results in aesthetically superior outcome and faster reepithelialization.