Thorac Cardiovasc Surg 2017; 65(03): 166-173
DOI: 10.1055/s-0036-1580622
Original Cardiovascular
Georg Thieme Verlag KG Stuttgart · New York

Surgical Treatment for Infective Endocarditis: A Single-Centre Experience

Sossio Perrotta
1   Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
2   Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
,
Anders Jeppsson
1   Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
2   Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
,
Victoria Fröjd
2   Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
,
Gunnar Svensson
1   Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
2   Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
› Institutsangaben
Weitere Informationen

Publikationsverlauf

25. September 2015

12. Februar 2016

Publikationsdatum:
13. April 2016 (online)

Abstract

Background A considerable proportion of patients with acute infective endocarditis require surgical treatment. The aim of this study was to collate our short- and medium-term results of surgical treatment of infective endocarditis and to compare the results in native and prosthetic endocarditis.

Method Total 254 operations for infective endocarditis from January 2008 to May 2015 were included in this retrospective study. There were 182 operations for native valve endocarditis and 72 for prosthetic valve endocarditis. Patient characteristics, operative details, complications, and mortality were registered.

Results The endocarditis was left sided in 247 operations (146 aortic, 78 mitral, and 23 double-valve) and right-sided in 7 (5 tricuspid and 2 pulmonary). Twenty-two patients (8.7%) died within 30 days (7.7% with native valve endocarditis and 11.1% with prosthetic valve endocarditis, p = 0.31). Severe perioperative complications occurred in 99 of 254 operations (39%). Overall cumulative survival at 1 and 5 years was 86% and 75%, respectively, and it was not significantly different for native and prosthetic endocarditis (p = 0.31). Eighteen patients (8%) had one (n = 16) or two (n = 2) recurrent episodes of endocarditis requiring surgery.

Conclusion Surgery for infective endocarditis is still associated with a high early mortality rate and a considerable complication rate. Long-term outcome is acceptable. In our study population, morbidity and mortality were not significantly different in native and prosthetic endocarditis.

 
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