Diabetologie und Stoffwechsel 2016; 11 - P221
DOI: 10.1055/s-0036-1580968

Cross-sectional survey study to understand behaviours, thoughts and perceptions of Mealtime Insulin (MTI) usage in patients with Type 1 and Type 2 Diabetes (T1D, T2D)

K van Brunt 1, SM Corrigan 2, R Pedersini 3, J Rooney 4
  • 1Eli Lilly & Company, Windlesham, United Kingdom
  • 2Eli Lilly & Company, Indianapolis, United States
  • 3Kantar Health, Epsom, United Kingdom
  • 4Kantar Health, New York, United States

Objectives: To estimate the average number of MTI units discarded per pen/cartridge by patients with diabetes taking > 20 units/day, based on injection habits when insufficient insulin remains in a pen/cartridge to administer a full dose in a single injection.

Methods: Cross-sectional, online, self-reported survey of MTI usage and wastage behaviours in adults with T1D or T2D who were members of the Lightspeed Panel (survey recruitment company) and using > 20 units/day of MTI administered via 100 units/mL pen/cartridge for ≥1 month, conducted from February–March 2015 in France, Germany, Italy, and UK.

Results: 400 patients with diabetes (120 T1D; 280 T2D) completed the survey. Mean age (SD) was 54.5 (12.2) years. Average BMI was 29.9 (7.2)kg/m2 (T1D: 26.9 [4.9]; T2D: 31.3 [7.7]). Average time since diabetes diagnosis was 16.1 (11.7) years (T1D: 23.4 [14.2]; T2D: 13.0 [8.8]). Total average MTI units taken per day (self-reported number of units taken at breakfast, lunch, and dinner combined) was 54.8 (34.1) units (T1D: 41.1 [21.9]; T2D: 60.6 [36.7]). 255 patients (63.8%) reported wasting no insulin, whereas 145 patients (36.3%) reported wasting some insulin. On average, patients reported discarding 2.0 (95% CI: 1.4 – 2.5) pens/cartridges per month that still had insulin remaining, leading to wastage of average 8.6 (95% CI: 7.2 – 10.0) units of MTI per pen/cartridge.

Conclusions: Every month, some unused insulin remained in the discarded pen in more than one third of patients taking > 20 units/day MTI. Higher strength MTI formulations providing fewer pen/cartridge transitions and improved patient education may help to reduce insulin wastage.