Download PDF
CC BY-NC-ND 4.0 · Indian Journal of Neurosurgery 2017; 06(01): 020-026
DOI: 10.1055/s-0036-1582433
Short Illustrative Review
Thieme Medical and Scientific Publishers Private Ltd.

Four Cases of Hemangiopericytoma and the Contribution of Radiotherapy in Their Management

Bhargavi Ilangovan
1   Department of Radiation Oncology, Apollo Speciality Hospitals, Chennai, Tamil Nadu, India
,
Neetu Sasikumar
1   Department of Radiation Oncology, Apollo Speciality Hospitals, Chennai, Tamil Nadu, India
,
Janos Stumpf
1   Department of Radiation Oncology, Apollo Speciality Hospitals, Chennai, Tamil Nadu, India
,
Rathna Devi
1   Department of Radiation Oncology, Apollo Speciality Hospitals, Chennai, Tamil Nadu, India
,
Murli Venkatraman
2   Department of Medical Physics, Apollo Speciality Hospitals, Chennai, Tamil Nadu, India
,
S. Kalyanaraman
3   Department of Neurosurgery, Apollo Speciality Hospitals, Chennai, Tamil Nadu, India
,
Chendhilnathan › Author Affiliations
Further Information

Publication History

06 April 2015

25 May 2015

Publication Date:
13 July 2016 (online)

   Permissions and Reprints

Abstract

Hemangiopericytomas are tumors arising from the Zimmerman pericytes. They are characterized by their propensity to recur aggressively and metastasize. Surgery forms the primary treatment modality. Radiotherapy has been used in the postoperative setting and has proved to produce a significant progression-free survival in cases with residual disease. Radiotherapy has been applied even as a single modality treatment whenever surgery could not be performed. We are presenting four cases of meningeal hemangiopericytomas which have been treated with radiotherapy in combination with surgery. These cases show various scenarios in which Radiotherapy has been used in hemangiopericytoma: adjuvant setting, residual/recurrent setting, and in the palliative setting. As far as the technique is concerned, three-dimensional conformal radiotherapy, fractionated radiosurgery, and other forms of high-precision irradiation (intensity-modulated radiation therapy [IMRT]) were given.

Keywords

hemangiopericytoma - radiotherapy - radiosurgery
 

  • References

  • 1 Stout AP, Murray MR. Hemagiopericytoma: vascular tumor featuring Zimmerman's pericytes. Ann Surg 1942; 116 (01) 26-33
    CrossrefPubMedGoogle Scholar
  • 2 Enzinger FM, Smith BH. Hemangiopericytoma. An analysis of 106 cases. Hum Pathol 1976; 7 (01) 61-82
    CrossrefPubMedGoogle Scholar
  • 3 Mena H, Ribas JL, Pezeshkpour GH, Cowan DN, Parisi JE. Hemangiopericytoma of the central nervous system: a review of 94 cases. Hum Pathol 1991; 22 (01) 84-91
    CrossrefPubMedGoogle Scholar
  • 4 Lamar Z, Lesser GJ. Management of meningeal neoplasms: meningiomas and hemangiopericytomas. Curr Treat Options Oncol 2011; 12 (03) 230-239
    CrossrefPubMedGoogle Scholar
  • 5 Nunnery EW, Kahn LB, Reddick RL, Lipper S. Hemangiopericytoma: a light microscopic and ultrastructural study. Cancer 1981; 47 (05) 906-914
    CrossrefPubMedGoogle Scholar
  • 6 Staples JJ, Robinson RA, Wen BC, Hussey DH. Hemangiopericytoma—the role of radiotherapy. Int J Radiat Oncol Biol Phys 1990; 19 (02) 445-451
    CrossrefPubMedGoogle Scholar
  • 7 Mira JG, Chu FC, Fortner JG. The role of radiotherapy in the management of malignant hemangiopericytoma: report of eleven new cases and review of the literature. Cancer 1977; 39 (03) 1254-1259
    CrossrefPubMedGoogle Scholar
  • 8 Coffey RJ, Cascino TL, Shaw EG. Radiosurgical treatment of recurrent hemangiopericytomas of the meninges: preliminary results. J Neurosurg 1993; 78 (06) 903-908
    CrossrefPubMedGoogle Scholar
  • 9 Guthrie BL, Ebersold MJ, Scheithauer BW, Shaw EG. Meningeal hemangiopericytoma: histopathological features, treatment, and long-term follow-up of 44 cases. Neurosurgery 1989; 25 (04) 514-522
    CrossrefPubMedGoogle Scholar