Tight Glycemic Control in the Pediatric Intensive Care Unit

Abstract

Hyperglycemia is a common complication in critically ill, nondiabetic children. Four large pediatric randomized controlled trials of tight glycemic control (TGC) have been conducted to date with contradicting results. This review will highlight the design and outcomes of these trials and other relevant studies to provide an overview of the advantages and disadvantages of TGC for different populations at risk of hyperglycemia along with future directions for research.

Keywords

tight glycemic control - intensive insulin therapy - pediatrics - hyperglycemia - critical illness hyperglycemia - stress hyperglycemia - hypoglycemia

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