Correlation of Menopausal Symptoms and Quality of Life with Physical Performance in Middle-Aged Women

Abstract

Introduction Some studies have investigated the influence of hormonal deficits and menopausal status in muscle disorders of women. However, it has not been investigated the relationship of both climacteric symptoms and the perception of quality of life with physical performance.

Objective To evaluate the correlation of menopausal symptoms and quality of life with physical performance in middle-aged women.

Methods This cross-sectional study was performed from April to November 2013 in the municipality of Parnamirim, in the Brazilian state, Rio Grande do Norte. The sample was composed of 497 women aged 40–65 years. The Menopause Rating Scale (MRS) and the Utian Quality of Life (UQOL) questionnaire were used to evaluate menopausal symptoms and quality of life respectively. Measures of physical performance included handgrip strength, knee extensor and flexor strengths (using an isometric dynamometer), gait speed, and chair stand test. The correlation between menopausal symptoms and quality of life with physical performance was assessed by Pearson's correlation coefficient with significance set at p < 0.05 and a confidence interval of 95%.

Results There was a significant negative correlation between handgrip strength and somatic MRS score (p = 0.002) and total MRS score (p = 0.03). There was a significant correlation between knee flexor strength and sit-to-stand time and all menopausal symptom areas (p < 0.05), except psychological symptoms. There was a positive correlation between physical performance of the knee flexors and quality of life items including occupational (p = 0.001), emotional (p = 0.005), and total UQOL (p = 0.01), but a negative correlation with sit-to-stand time and all quality of life domains (p < 0.05).

Conclusion A greater intensity of menopausal symptoms and worse quality of life were related with worse physical performance. Thus, preventive measures should be implemented to avoid adverse effects on physical performance at more advanced ages.

Resumo

Objetivo Avaliar a relação entre sintomatologia climatérica e qualidade de vida no desempenho físico em mulheres de meia-idade.

Métodos Estudo transversal, realizado de abril a novembro de 2013, no município de Parnamirim/RN. A amostra foi composta por 497 mulheres (40 a 65 anos). Menopause Rating Scale (MRS) foi utilizada para a avaliação dos sintomas climatéricos e Utian Quality of Life (UQOL) para a qualidade de vida. Medidas de desempenho físico foram compostas pela força de preensão manual, força de extensores e flexores de joelho (usando um dinamômetro isométrico), velocidade de marcha e tempo de sentar-levantar. A relação da sintomatologia climatérica e qualidade de vida com o desempenho físico foi avaliada pelo teste de correlação de Pearson, sendo considerado um p < 0,05 e intervalo de confiança de 95%.

Resultados Houve correlação significativa negativa da força de preensão quanto ao MRS somático (p = 0,002) e total (p = 0,03). Para força de flexores de joelho e tempo de sentar-levantar, houve correlação significativa para todos os domínios dos sintomas climatéricos (p < 0,05), exceto o psicológico. Entre qualidade de vida e desempenho físico, houve correlação positiva dos flexores de joelho quanto ao UQOL ocupacional (p = 0,001), emocional (p = 0,005) e total (p = 0,01), e negativa para o teste sentar-levantar quanto a todos os domínios (p < 0,05).

Conclusão A maior intensidade dos sintomas climatéricos e a pior qualidade de vida apresentaram relação com piores desempenhos. Dessa forma, medidas de prevenção devem ser implementadas a fim de evitar consequências negativas no desempenho físico em idades mais avançadas.

Keywords

menopause - quality of life - muscle strength

Palavras-chave

climatério - qualidade de vida - força muscular

• References

• 1 Messier V, Rabasa-Lhoret R, Barbat-Artigas S, Elisha B, Karelis AD, Aubertin-Leheudre M. Menopause and sarcopenia: A potential role for sex hormones. Maturitas 2011; 68 (4) 331-336
• 2 Instituto Brasileiro de Geografia e Estatística [Internet]. Expectativa de vida. 2013 [citado 2015 Jun 13]. Disponível em: http://teen.ibge.gov.br/noticias-teen/7827-expectativa-de-vida
• 3 da Câmara SM, Zunzunegui MV, Pirkle C, Moreira MA, Maciel ACC. Menopausal status and physical performance in middle aged women: a cross-sectional community-based study in Northeast Brazil. PLoS ONE 2015; 10 (3) e0119480
• 4 Orsatti FL, Dalanesi RC, Maestá N, Náhas EAP, Burini RC. Redução da força muscular está relacionada à perda muscular em mulheres acima de 40 anos. Rev Bras Cineantropom Desempenho Hum. 2011; 13 (1) 36-42
• 5 Ferreira VN, Chinelato RSC, Castro MR, Ferreira MEC. [Menopause: biopsychossocial landmark of female aging]. Psicol Soc 2013; 25 (2) 410-419 Portuguese.
• 6 Lorenzi DR, Catan LB, Moreira K, Ártico GR. Assistance to the climacteric woman: new paradigms. Rev Bras Enferm 2009; 62 (2) 287-293
• 7 Cheng MH, Wang SJ, Yang FY, Wang PH, Fuh JL. Menopause and physical performance—a community-based cross-sectional study. Menopause 2009; 16 (5) 892-896
• 8 De Lorenzi DRS, Baracat EC, Saciloto B, Padilha Jr I. Factors related to quality of life in post-menopause. Rev Assoc Med Bras 2006; 52 (5) 312-317
• 9 Guimarães ACA, Baptista F. Relationship between physical activity and menopausal symptoms. Rev Bras Ativ Fís Saúde. 2011; 16 (2) 144-149
• 10 Brito NMB, Tavares NCS, Macedo LFC, Gonçalves BK. [Evaluation of the quality of life of climateric patients in a unit of health]. Rev Para Med. 2009; 23 (2) 1-7 Portuguese.
• 11 De Lorenzi DRS, Danelon C, Saciloto B, Padilha Júnior I. [Predicting factors of climacteric symptoms]. Rev Bras Ginecol Obstet 2005; 27 (1) 7-11 Portuguese.
• 12 Aldrighi JM, Aldrighi CMS, Aldrighi APS. [Sistemic changes in climacterium]. Rev Bras Med 2002; 59 (4) 15-21 Portuguese.
• 13 Pierine DT, Nicola M, Oliveira EP. Sarcopenia: alterações metabólicas e consequências no envelhecimento. Rev Bras Ciênc Mov. 2009; 17 (3) 96-103
• 14 Cooper R, Mishra G, Clennell S, Guralnik J, Kuh D. Menopausal status and physical performance in midlife: findings from a British birth cohort study. Menopause 2008; 15 (6) 1079-1085
• 15 Fess EE. Grip strength. In: American Society of Hand Therapists. Clinical assessment recommendations. 2nd ed. Chicago: The Society; 1992. . p. 41-45
• 16 Martin HJ, Yule V, Syddall HE, Dennison EM, Cooper C, Aihie Sayer A. Is hand-held dynamometry useful for the measurement of quadriceps strength in older people? A comparison with the gold standard Bodex dynamometry. Gerontology 2006; 52 (3) 154-159
• 17 Guralnik JM, Simonsick EM, Ferrucci L , et al. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 1994; 49 (2) M85-M94
• 18 Heinemann K, Ruebig A, Potthoff P , et al. The Menopause Rating Scale (MRS) scale: a methodological review. Health Qual Life Outcomes 2004; 2: 45
• 19 Utian WH, Janata JW, Kingsberg SA, Schluchter M, Hamilton JC. The Utian Quality of Life (UQOL) Scale: development and validation of an instrument to quantify quality of life through and beyond menopause. Menopause 2002; 9 (6) 402-410
• 20 Galvão LLLF. Tradução, adaptação e validação da versão brasileira do questionário utian quality of life (uqol) para avaliação da qualidade de vida no climatério [dissertação]. Natal: Universidade Federal do Rio Grande do Norte; 2007
• 21 Matsudo S, Araújo T, Matsudo V , et al. Questionário Internacional de Atividade Física (IPAQ): estudo de validade e reprodutibilidade no Brasil. Rev Bras Ativ Fís Saúde. 2001; 6 (2) 5-18
• 22 Rolland YM, Perry III HM, Patrick P, Banks WA, Morley JE. Loss of appendicular muscle mass and loss of muscle strength in young postmenopausal women. J Gerontol A Biol Sci Med Sci 2007; 62 (3) 330-335
• 23 da Silveira Gonçalves AK, Gomes Canário AC, Leitão Cabral PU , et al. Impact of physical activity on quality of life in middle-aged women: a population based study. Rev Bras Ginecol Obstet 2011; 33 (12) 408-413
• 24 Llanas AC, Hachul H, Bittencourt LRA, Tufik S. Physical therapy reduces insomnia symptoms in postmenopausal women. Maturitas 2008; 61 (3) 281-284
• 25 Nachtigall LE, Nachtigall MJ. Menopausal changes, quality of life, and hormone therapy. Clin Obstet Gynecol 2004; 47 (2) 485-488
• 26 Presado MHCV. Climatério/menopausa, relacionamento conjugal e qualidade de vida [tese]. Lisboa: Universidade Aberta; 2013
• 27 Penttinen HM, Saarto T, Kellokumpu-Lehtinen P , et al. Quality of life and physical performance and activity of breast cancer patients after adjuvant treatments. Psychooncology 2011; 20 (11) 1211-1220
• 28 Gomes CdosS, Maciel ACC, Freire AdoN, Moreira MdeA, Ribeiro MdeO, Guerra RO. Depressive symptoms and functional decline in an elderly sample of urban center in Northeastern Brazil. Arch Gerontol Geriatr 2014; 58 (2) 214-218
• 29 Lee JY, Lee DC. Muscle strength and quality are associated with severity of menopausal symptoms in peri- and post-menopausal women. Maturitas 2013; 76 (1) 88-94
• 30 World Health Organization [Internet]. International classification of impairments, disabilities, and handicaps: a manual of classification relating to the consequences of disease: published in accordance with resolution WHA29.35 of the Twenty-ninth World Health Assembly, May 1976. Geneva: World Health Organization; 1980 [cited 2015 May 18]. Available from: http://www.who.int/iris/handle/10665/41003
• 31 Dennerstein L, Helmes E. The menopausal transition and quality of life : methodologic issues. Qual Life Res 2000; 9 (Suppl. 01) 721-731
• 32 Haring R, Feng YS, Moock J , et al. Self-perceived quality of life predicts mortality risk better than a multi-biomarker panel, but the combination of both does best. BMC Med Res Methodol 2011; 11: 103
• 33 Sasaki H, Kasagi F, Yamada M, Fujita S. Grip strength predicts cause-specific mortality in middle-aged and elderly persons. Am J Med 2007; 120 (4) 337-342
• 34 Studenski S, Perera S, Patel K , et al. Gait speed and survival in older adults. JAMA 2011; 305 (1) 50-58
• 35 Kuh D, Bassey EJ, Butterworth S, Hardy R, Wadsworth MEJ ; Musculoskeletal Study Team. Grip strength, postural control, and functional leg power in a representative cohort of British men and women: associations with physical activity, health status, and socioeconomic conditions. J Gerontol A Biol Sci Med Sci 2005; 60 (2) 224-231