DOI: 10.1055/s-0036-1588474
© Georg Thieme Verlag Stuttgart · New York

A Borane-Catalyzed Metal-Free Hydrosilylation of Chromones and Flavones

Xiaoyu Rena, b, Caifang Hana, b, c, Xiangqing Fenga, b, Haifeng Du*a, b
  • aBeijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. of China   Email:
  • bUniversity of Chinese Academy of Sciences, Beijing 100049, P. R. of China
  • cCollege of Chemistry and Material Sciences, Hebei Normal University, Shijiazhuang, Hebei 050024, P. R. of China
We are grateful for the generous financial support by the National Natural Science Foundation of China (21222207, 21572231, 21521002).
Further Information

Publication History

Received: 28 April 2017

Accepted after revision: 29 May 2017

Publication Date:
06 July 2017 (eFirst)

Published as part of the Cluster Silicon in Synthesis and Catalysis


A Piers-type hydrosilylation of chromones and flavones has been successfully realized for the first time using 0.1 mol % of borane catalyst generated in situ by hydroboration of pentafluorostyrene with HB(C6F5)2 to afford a variety of chromanones and flavanones in 60–99% yields. An attempt for the asymmetric transformation with chiral diyne and HB(C6F5)2 gave chromanones and flavanones in high yields with up to 32% ee.

Supporting Information