Synlett 2017; 28(17): 2272-2276
DOI: 10.1055/s-0036-1588482
letter
© Georg Thieme Verlag Stuttgart · New York

Copper-Catalyzed Direct Synthesis of Aryl Thiols from Aryl Iodides Using Sodium Sulfide Aided by Catalytic 1,2-Ethanedithiol

Hongyu Xuea, Bing Jinga, Shasha Liua, Junghyun Chae*b, Yajun Liu*a
  • aCollege of Life Science and Medicine, Dalian University of Technology, Panjin 124221, P. R. of China   Email: yjliu85@dlut.edu.cn
  • bDepartment of Chemistry and Research Institute of Basic Sciences, Sungshin Women’s University, Seoul 136-742, South Korea   Email: jchae@sungshin.ac.kr
We gratefully acknowledge the financial support by the Fundamental Research Funds for the Central Universities (DUT15RC(3)043; DUT17LK23), National Research Foundation of Korea (Basic Science Research Program Fund: NRF2015R1D1A1A01060188).
Further Information

Publication History

Received: 21 May 2017

Accepted after revision: 07 June 2017

Publication Date:
18 July 2017 (eFirst)

Abstract

A copper-catalyzed direct and effective synthesis of aryl thiols from aryl iodides using readily available Na2S·9H2O and 1,2-ethanedithiol was described. A variety of aryl thiols were readily obtained in yields of 76–99%. In this protocol, Na2S·9H2O was used as ultimate sulfur source, and 1,2-ethanedithiol functioned as an indispensable catalytic reagent.

Supporting Information