Domino Reactions of 1-Aroyl-3,4-dihydroisoquinolines with α,β-Unsaturated AldehydesThis work was supported by the Russian Foundation for Basic Research (grant 17-03-00605) and was financially supported by the Ministry of Education and Science of the Russian Federation (agreement no. 02.a03.21.0008).
Received: 16 April 2017
Accepted after revision: 12 June 2017
22 August 2017 (eFirst)
An efficient synthesis of pyrrolo[2,1-a]isoquinolines by a domino reaction from a variety of 3,4-dihydropyrrolo[2,1-a]isoquinolines and α,β-unsaturated aldehydes in the absence of catalyst in good yields under microwave irradiation, is reported.