Palladium-Catalyzed Regio- and Stereoselective Hydrosulfonation of Propiolate EstersMinistry of Science and Technology of Taiwan (MOST104-2113-M-009-014-MY3 and MOST105-2628-M-009-002-MY3)
Received: 15 April 2017
Accepted after revision: 09 June 2017
31 July 2017 (eFirst)
An efficient palladium-catalyzed addition reaction of alkyl- and arylsulfonic acids to propiolate esters to yield alkenyl sulfonates is demonstrated. The formation of alkenyl sulfonates is highly regio- and stereoselective with favorable yields of up to 95%, and two of the alkenyl sulfonates are utilized for a Sonogashira cross-coupling reaction to produce (Z)-1,3-enynoates.