Synlett 2017; 28(18): 2505-2508
DOI: 10.1055/s-0036-1588529
letter
© Georg Thieme Verlag Stuttgart · New York

Nonenzymatic Biomimetic Synthesis of Black Tea Pigment Theaflavins

Yosuke Matsuo*, Ryosuke Oowatashi, Yoshinori Saito, Takashi Tanaka*
This work was supported by JSPS KAKENHI Grant Numbers JP16K07741 and JP17K08338
Further Information

Publication History

Received: 07 June 2017

Accepted after revision: 04 July 2017

Publication Date:
11 August 2017 (eFirst)

Abstract

Theaflavins are reddish-orange black tea pigments with a benzotropolone chromophore, and their various biological activities have been reported. Theaflavins are produced by oxidative coupling between catechol-type and pyrogallol-type catechins via bicyclo[3.2.1]octane-type intermediates. In this study, a new method for nonenzymatic biomimetic synthesis of theaflavins was developed using the DPPH radical as an oxidizing agent.

Supporting Information

 
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