Nonenzymatic Biomimetic Synthesis of Black Tea Pigment TheaflavinsThis work was supported by JSPS KAKENHI Grant Numbers JP16K07741 and JP17K08338
Received: 07 June 2017
Accepted after revision: 04 July 2017
11 August 2017 (eFirst)
Theaflavins are reddish-orange black tea pigments with a benzotropolone chromophore, and their various biological activities have been reported. Theaflavins are produced by oxidative coupling between catechol-type and pyrogallol-type catechins via bicyclo[3.2.1]octane-type intermediates. In this study, a new method for nonenzymatic biomimetic synthesis of theaflavins was developed using the DPPH radical as an oxidizing agent.