N-Arylation of Heterocycles by a Tandem Aza-Michael Addition Reaction and Aromatization Sequence
Received: 02 June 2017
Accepted after revision: 13 July 2017
17 August 2017 (eFirst)
Cyclohexa-2,4-dien-1-one derivatives, upon reaction with N-heterocycles in the presence of scandium(III) triflate, underwent a tandem Michael addition reaction followed by aromatization of the Michael adduct generated in situ to give N-aryl heterocycles in good yields. Because of the ready accessibility of variously substituted cyclohexa-2,4-dien-1-ones, a range of N-aryl heterocycles have become available.