Tf2NH-Catalyzed 1,6-Conjugate Addition of Vinyl Azides with p-Quinone Methides: A Mild and Efficient Method for the Synthesis of β-Bis-ArylamidesJ. R and B. M. S thank the Council of Scientific and Industrial Research (CSIR), New Delhi for a Senior Research Fellowship. Dr. P. R. Rajamohanan [CSIR-NCL)] is thanked for NMR support, Ms. B. Santhakumari (CSIR-NCL) for the HRMS data; P. K also thanks the Council of Scientific and Industrial Research (CSIR), New Delhi for financial support as part of XII Five Year Plan under the title ORIGIN (CSC0108).
Received: 19 July 2017
Accepted after revision: 19 July 2017
22 August 2017 (eFirst)
Tf2NH-catalyzed tandem 1,6-conjugate addition/Schmidt type rearrangement using vinyl azides and p-quinone methides to access a variety of β-bis-arylated amides is reported. The method is quick, efficient, mild, and high yielding with broad substrate scope.