Synthesis
DOI: 10.1055/s-0036-1588555
short review
© Georg Thieme Verlag Stuttgart · New York

Indium(III)-Catalyzed Transformations of Alkynes: Recent Advances in Carbo- and Heterocyclization Reactions

Stalin R. Pathipati, Angela van der Werf, Nicklas Selander*
  • Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, 106 91 Stockholm, Sweden   Email: nicklas.selander@su.se
Financial support from the Swedish Research Council (2012-2981) is gratefully acknowledged.
Further Information

Publication History

Received: 29 June 2017

Accepted after revision: 27 July 2017

Publication Date:
30 August 2017 (eFirst)

Abstract

The use of a well-chosen catalyst is instrumental for the development of more efficient, economical and environmentally friendly reactions. In recent decades, indium-based catalysts have proven to be competitive and useful alternatives to transition-metal catalysts such as silver and gold. In this short review, we present some of the recent advances in indium(III)-catalyzed transformations of alkynes, with a focus on cyclization reactions.

1 Introduction

2 Terminal Alkynes as Nucleophiles

3 Nucleophilic Additions to Alkynes

4 Carbo- and Heterocyclization Reactions

4.1 Carbocyclization

4.2 Oxygen-Based Heterocycles

4.3 Nitrogen-Based Heterocycles

4.4 Sulfur-Based Heterocycles

5 Conclusion