Synthesis 2017; 49(01): 145-150
DOI: 10.1055/s-0036-1588589
paper
© Georg Thieme Verlag Stuttgart · New York

Organocatalytic Alkyne Isomerizations under Flow Conditions Using Heterogeneous Bifunctional Polystyrene Bearing Phosphine and Phenol Groups

Sascha Ceylan
a  Institute of Organic Chemistry and Center of Biomolecular Drug Research (BMWZ), Leibniz Universität Hannover, Schneiderberg 1b, 30167 Hannover, Germany   Email: andreas.kirschning@oci.uni-hannover.de
,
Henry Chun-Hin Law
b  Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. of China   Email: phtoy@hku.hk
,
Andreas Kirschning*
a  Institute of Organic Chemistry and Center of Biomolecular Drug Research (BMWZ), Leibniz Universität Hannover, Schneiderberg 1b, 30167 Hannover, Germany   Email: andreas.kirschning@oci.uni-hannover.de
,
Patrick H. Toy*
b  Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. of China   Email: phtoy@hku.hk
› Author Affiliations
Further Information

Publication History

Received: 27 June 2016

Accepted after revision: 05 August 2016

Publication Date:
10 October 2016 (eFirst)

Abstract

A heterogeneous bifunctional polymer bearing phosphine and phenol groups was developed to catalyze the isomerization of electronically activated alkynes. This organocatalytic process provided the corresponding (E,E)-dienes and was shown to work under both batch and flow conditions.

Supporting Information

 
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