Organocatalytic Alkyne Isomerizations under Flow Conditions Using Heterogeneous Bifunctional Polystyrene Bearing Phosphine and Phenol Groups

Abstract

A heterogeneous bifunctional polymer bearing phosphine and phenol groups was developed to catalyze the isomerization of electronically activated alkynes. This organocatalytic process provided the corresponding (E,E)-dienes and was shown to work under both batch and flow conditions.

Key words

rearrangement - organocatalysis - polymer-supported catalyst - phosphine - phenols - flow chemistry

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