Synlett 2017; 28(13): 1501-1509
DOI: 10.1055/s-0036-1588827
synpacts
© Georg Thieme Verlag Stuttgart · New York

Lewis Acid Catalyzed Carbonyl–Olefin Metathesis

Jacob R. Ludwig
Willard Henry Dow Laboratory, Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109, USA   Email: corinnas@umich.edu
,
Corinna S. Schindler*
Willard Henry Dow Laboratory, Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109, USA   Email: corinnas@umich.edu
› Author Affiliations
We thank the Petroleum Research Fund (PRF#54688-DNI1), the University of Michigan Office of Research, and the NIH/National Institute of General Medical Sciences (GM118644) for financial support. C.S.S. thanks the David and Lucile Packard Foundation. J.R.L. thanks the National Science Foundation for a predoctoral fellowship.
Further Information

Publication History

Received: 27 February 2017

Accepted after revision: 10 April 2017

Publication Date:
16 May 2017 (online)

Abstract

Olefin–olefin metathesis has led to important advances in diverse fields of research, including synthetic chemistry, materials science, and chemical biology. The corresponding carbonyl–olefin metathesis also enables direct carbon–carbon bond formation from readily available precursors, however, currently available synthetic procedures are significantly less advanced. This Synpacts article provides an overview of recent achievements in the field of Lewis acid mediated and Lewis acid catalyzed carbonyl–olefin metathesis reactions.

1 Lewis Acid Mediated Carbonyl–Olefin Metathesis

2 Lewis Acid Catalyzed Carbonyl–Olefin Metathesis

 
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