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Synfacts 2016; 12(10): 1001
DOI: 10.1055/s-0036-1589191
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Vismodegib through meta-Selective Nitration of Arenes

Contributor(s):
Philip Kocienski
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Publication History

Publication Date:
19 September 2016 (online)

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Key words

vismodegib - C–H activation - ruthenium catalysis - meta nitration - ortho metalation - palladium catalysis