Synthesis
DOI: 10.1055/s-0036-1590889
short review
© Georg Thieme Verlag Stuttgart · New York

Recent Advances in the Chemistry of 2-Acylaziridines

Alena S. Pankova*, Mikhail A. Kuznetsov*
  • Institute of Chemistry, Saint Petersburg State University, Universitetsky pr. 26, 198504 Saint Petersburg, Russian Federation   Email: a.pankova@spbu.ru   Email: m.kuznetsov@spbu.ru
The authors thank the Ministry of Education and Science of the Russian­ Federation for the financial support (grant of the President of the Russian Federation no. MK-5965.2016.3).
Further Information

Publication History

Received: 19 June 2017

Accepted after revision: 31 July 2017

Publication Date:
06 September 2017 (eFirst)

Abstract

This review highlights recent achievements in the transformations of 2-acylaziridines toward the synthesis of cyclic and acyclic nitrogen-containing compounds. The influence of a carbonyl group on reaction selectivity is discussed.

1 Introduction

2 Reactions via C–C Bond Cleavage

3 Reactions via C–N Bond Cleavage

3.1 Reactions Starting with the Aziridine Ring Opening

3.2 Reactions Starting at the Carbonyl Group

4 Conclusion