Synthesis
DOI: 10.1055/s-0036-1590895
paper
© Georg Thieme Verlag Stuttgart · New York

Recycled Pd/C-Catalyzed Heck Reaction of 2-Iodoanilines under Ligand-Free Conditions

Xiao-Yu Zhou*a, Xia Chen*a, Liang-Guang Wangb
  • aCollege of Chemistry and Materials Engineering, Liupanshui Normal University, Liupanshui, 553004, P. R. of China   Email: zhouxiaoyu20062006@126.com
  • bCollege of Chemistry and Chemical Engineering, Anshun University, Anshun, 561000, P. R. of China
The work was supported by the Youth Science and Technology Talent Development Project in the Education Department of Guizhou Province (Grant No.qianjiaohe KY zi [2016] number 263) and by the Innovation Team of Liupanshui Normal University (Grant No. LPSSYKJTD201601).
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Publication History

Received: 27 June 2017

Accepted after revision: 07 August 2017

Publication Date:
28 August 2017 (eFirst)

Abstract

Recyclable Pd/C-catalyzed Heck reaction of 2-iodoanilines with acrylate has been developed. The reaction occurred readily in 1,4-dioxane using Pd/C (10 wt%) as catalyst under ligand-free conditions, and the cross-coupling products were obtained with medium to high yield. Gram-scale reactions and recycling of the catalyst were also demonstrated.

Supporting Information