Synthesis 2017; 49(24): 5364-5370
DOI: 10.1055/s-0036-1590895
paper
© Georg Thieme Verlag Stuttgart · New York

Recycled Pd/C-Catalyzed Heck Reaction of 2-Iodoanilines under Ligand-Free Conditions

Xiao-Yu Zhou*
College of Chemistry and Materials Engineering, Liupanshui Normal University, Liupanshui, 553004, P. R. of China   Email: zhouxiaoyu20062006@126.com
,
Xia Chen*
College of Chemistry and Materials Engineering, Liupanshui Normal University, Liupanshui, 553004, P. R. of China   Email: zhouxiaoyu20062006@126.com
,
Liang-Guang Wang
College of Chemistry and Chemical Engineering, Anshun University, Anshun, 561000, P. R. of China
› Author Affiliations
The work was supported by the Youth Science and Technology Talent Development Project in the Education Department of Guizhou Province (Grant No.qianjiaohe KY zi [2016] number 263) and by the Innovation Team of Liupanshui Normal University (Grant No. LPSSYKJTD201601).
Further Information

Publication History

Received: 27 June 2017

Accepted after revision: 07 August 2017

Publication Date:
28 August 2017 (eFirst)

Abstract

Recyclable Pd/C-catalyzed Heck reaction of 2-iodoanilines with acrylate has been developed. The reaction occurred readily in 1,4-dioxane using Pd/C (10 wt%) as catalyst under ligand-free conditions, and the cross-coupling products were obtained with medium to high yield. Gram-scale reactions and recycling of the catalyst were also demonstrated.

Supporting Information

 
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