Synfacts, Table of Contents Synfacts 2017; 13(12): 1234DOI: 10.1055/s-0036-1591623 Synthesis of Natural Products and Potential Drugs © Georg Thieme Verlag Stuttgart · New YorkAsymmetric Transfer Hydrogenation in the Synthesis of Lorlatinib Authors Contributor(s): Philip Kocienski Recommend Article Abstract Buy Article(opens in new window)Key words Key wordsLorlatinib - ALK inhibitor - Noyori asymmetric transfer hydrogenation - directed ortho-metalation - ketoreductase Full Text