Geburtshilfe Frauenheilkd 2016; 76 - P089
DOI: 10.1055/s-0036-1592993

The metastatic behaviour between peritumoral lymphagiosis carcinomatosa and lymph nodes in breast cancer

G Macicasan 1, S Falk 2, E Lieb 1
  • 1Hospital zum Heiligen Geist, Gynäkologie, Frankfurt am Main, Deutschland
  • 2Institut für Pathologie, Frankfurt am Main, Deutschland

Introduction: Based on the central role of biomarkers in planning the mammary cancer therapy, we investigated 500 cases, randomly selected, to emphasize the relationship between peritumoral lymphangiosis and lymph node metastasis in breast cancer.

Materials and Method: We have selected cases that are ordered under the four molecular types.

We noticed that the majority of mammary carcinoma are part of the Luminal A and Luminal B subtypes, mainly Luminal A.

We observed that the peritumoral carcinomatose lymphangiosis in mammary cancer has a very important role in the metastasis process of lymph nodes:

  • The L1 status has a HIGH RISK of nodule METASTASIS (HRM)

  • The L0 status has a LOW METASTASIS RISK (LRM)

allowing that the size and biology of the tumor have favorable criteria.

Conclusions:

  • The presence of peritumoral lymphangiosis implies a direct relationship with the metastasis of lymph nodes and their increase in number.

  • Peritumoral lymphangiosis can be used as a prediction factor in a high or low risk metastasis of lymph nodes, as well as a prognostic factor.

  • In the case of tumors with a low metastatic risk, we can even forego the axial dissection. The decision must be taken in agreement with the patient, which must be rigorously informed about the intra/post-surgery complications, as well as the risks of relapse and tumoral metastasis in the context of comorbidity.