Clin Colon Rectal Surg 2017; 30(01): 030-039
DOI: 10.1055/s-0036-1593429
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Intestinal Intussusception: Etiology, Diagnosis, and Treatment

Priscilla Marsicovetere
1   Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
2   Geisel School of Medicine, Hanover, New Hampshire
,
S. Joga Ivatury
1   Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
2   Geisel School of Medicine, Hanover, New Hampshire
3   The Dartmouth Institute for Health Policy & Clinical Practice, Lebanon, New Hampshire
,
Brent White
1   Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
2   Geisel School of Medicine, Hanover, New Hampshire
,
Stefan D. Holubar
1   Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
2   Geisel School of Medicine, Hanover, New Hampshire
3   The Dartmouth Institute for Health Policy & Clinical Practice, Lebanon, New Hampshire
› Author Affiliations
Further Information

Publication History

Publication Date:
22 December 2016 (online)

Abstract

Intussusception is defined as the invagination of one segment of the bowel into an immediately adjacent segment of the bowel. Idiopathic ileocolic intussusception is the most common form in children and is typically managed with nonoperative reduction via pneumatic and/or hydrostatic enemas. In the adult population, intussusception is uncommon and occurs more often in the small intestine than in the colon. It is associated with lead point pathology in most symptomatic cases presenting as bowel obstruction. When lead point pathology is present in adult small bowel intussusception, it is usually benign, though when malignant it is most frequently due to diffuse metastatic disease, for example, melanoma. In contrast, adult ileocolic and colonic intussusception lead point pathology is most frequently primary adenocarcinoma when malignant. The diagnosis is typically made intraoperatively or by cross-sectional imaging. With increasingly frequent CT/MRI of the adult abdomen in the current era, transient and/or asymptomatic intussusceptions are increasingly found and may often be appropriately observed without intervention. When intervention in the adult population is warranted, usually oncologic bowel resection is performed due to the association with lead point pathology.

Note

The previous version of this article was authored by Susan M. Cera, MD.


 
  • References

  • 1 Lloyd DA, Kenny SE. The surgical abdomen. In: Walker WA, Goulet O, Kleinman RE, , et al, eds. Pediatric Gastrointestinal Disease: Pathophysiology, Diagnosis, Management. 4th ed. Ontario, Canada: BC Decker; 2004: 604
  • 2 Begos DG, Sandor A, Modlin IM. The diagnosis and management of adult intussusception. Am J Surg 1997; 173 (2) 88-94
  • 3 Scheye Th, Dechelotte P, Tanguy A, Dalens B, Vanneuville G, Chazai J. Anatomical and histological study of the ileocecal valve: possible correlations with the pathogenesis of idiopathic intussusception in infants. Surg Radiol Anat 1983; 5 (2) 83-92
  • 4 Buettcher M, Baer G, Bonhoeffer J, Schaad UB, Heininger U. Three-year surveillance of intussusception in children in Switzerland. Pediatrics 2007; 120 (3) 473-480
  • 5 Rao PL, Kumar V. Waugh's syndrome. Indian J Pediatr 2005; 72 (1) 86
  • 6 Al-Momani H. Waugh syndrome: a report of 7 patients and review of the published reports. Ann Saudi Med 2014; 34 (6) 527-531
  • 7 Eisen LK, Cunningham JD, Aufses Jr AH. Intussusception in adults: institutional review. J Am Coll Surg 1999; 188 (4) 390-395
  • 8 Azar T, Berger DL. Adult intussusception. Ann Surg 1997; 226 (2) 134-138
  • 9 Zubaidi A, Al-Saif F, Silverman R. Adult intussusception: a retrospective review. Dis Colon Rectum 2006; 49 (10) 1546-1551
  • 10 Wang LT, Wu CC, Yu JC, Hsiao CW, Hsu CC, Jao SW. Clinical entity and treatment strategies for adult intussusceptions: 20 years’ experience. Dis Colon Rectum 2007; 50 (11) 1941-1949
  • 11 VanderKolk WE, Snyder CA, Figg DM. Cecal-colic adult intussusception as a cause of intestinal obstruction in Central Africa. World J Surg 1996; 20 (3) 341-343 , discussion 344
  • 12 West KW, Stephens B, Vane DW, Grosfeld JL. Intussusception: current management in infants and children. Surgery 1987; 102 (4) 704-710
  • 13 Elm'hadi C, Tarchouli M, Khmamouche MR , et al. Intestinal intussusception in a young women: unusual cause and specific management. World J Surg Oncol 2015; 13: 252
  • 14 Mrak K. Uncommon conditions in surgical oncology: acute abdomen caused by ileocolic intussusception. J Gastrointest Oncol 2014; 5 (4) E75-E79
  • 15 McKay R. Ileocecal intussusception in an adult: the laparoscopic approach. JSLS 2006; 10 (2) 250-253
  • 16 Sarma D, Prabhu R, Rodrigues G. Adult intussusception: a six-year experience at a single center. Ann Gastroenterol 2012; 25 (2) 128-132
  • 17 Voore N, Weisner L. Unusual cause of intussusception. BMJ Case Rep 2015; 2015 DOI: 10.1136/bcr-2015-212324.
  • 18 Martín-Lorenzo JG, Torralba-Martinez A, Lirón-Ruiz R , et al. Intestinal invagination in adults: preoperative diagnosis and management. Int J Colorectal Dis 2004; 19 (1) 68-72
  • 19 Chiang JM, Lin YS. Tumor spectrum of adult intussusception. J Surg Oncol 2008; 98 (6) 444-447
  • 20 Guillén Paredes MP, Campillo Soto A, Martín Lorenzo JG , et al. Adult intussusception - 14 case reports and their outcomes. Rev Esp Enferm Dig 2010; 102 (1) 32-40
  • 21 Ratcliffe JF, Fong S, Cheong I, O'Connell P. Plain film diagnosis of intussusception: prevalence of the target sign. AJR Am J Roentgenol 1992; 158 (3) 619-621
  • 22 Saverino BP, Lava C, Lowe LH, Rivard DC. Radiographic findings in the diagnosis of pediatric ileocolic intussusception: comparison to a control population. Pediatr Emerg Care 2010; 26 (4) 281-284
  • 23 Weihmiller SN, Buonomo C, Bachur R. Risk stratification of children being evaluated for intussusception. Pediatrics 2011; 127 (2) e296-e303
  • 24 Wiersma F, Allema JH, Holscher HC. Ileoileal intussusception in children: ultrasonographic differentiation from ileocolic intussusception. Pediatr Radiol 2006; 36 (11) 1177-1181
  • 25 Boyle MJ, Arkell LJ, Williams JT. Ultrasonic diagnosis of adult intussusception. Am J Gastroenterol 1993; 88 (4) 617-618
  • 26 Ciftci F. Diagnosis and treatment of intestinal intussusception in adults: a rare experience for surgeons. Int J Clin Exp Med 2015; 8 (6) 10001-10005
  • 27 Yakan S, Caliskan C, Makay O, Denecli AG, Korkut MA. Intussusception in adults: clinical characteristics, diagnosis and operative strategies. World J Gastroenterol 2009; 15 (16) 1985-1989
  • 28 Lioubashevsky N, Hiller N, Rozovsky K, Segev L, Simanovsky N. Ileocolic versus small-bowel intussusception in children: can US enable reliable differentiation?. Radiology 2013; 269 (1) 266-271
  • 29 Munden MM, Bruzzi JF, Coley BD, Munden RF. Sonography of pediatric small-bowel intussusception: differentiating surgical from nonsurgical cases. AJR Am J Roentgenol 2007; 188 (1) 275-279
  • 30 Kim YH, Blake MA, Harisinghani MG , et al. Adult intestinal intussusception: CT appearances and identification of a causative lead point. Radiographics 2006; 26 (3) 733-744
  • 31 Rea JD, Lockhart ME, Yarbrough DE, Leeth RR, Bledsoe SE, Clements RH. Approach to management of intussusception in adults: a new paradigm in the computed tomography era. Am Surg 2007; 73 (11) 1098-1105
  • 32 Lvoff N, Breiman RS, Coakley FV, Lu Y, Warren RS. Distinguishing features of self-limiting adult small-bowel intussusception identified at CT. Radiology 2003; 227 (1) 68-72
  • 33 Jain P, Heap SW. Intussusception of the small bowel discovered incidentally by computed tomography. Australas Radiol 2006; 50 (2) 171-174
  • 34 Honjo H, Mike M, Kusanagi H, Kano N. Adult intussusception: a retrospective review. World J Surg 2015; 39 (1) 134-138
  • 35 Cakir M, Tekin A, Kucukkartallar T, Belviranli M, Gundes E, Paksoy Y. Intussusception: as the cause of mechanical bowel obstruction in adults. Korean J Gastroenterol 2013; 61 (1) 17-21