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Pneumologie 2017; 71(S 01): S1-S125
DOI: 10.1055/s-0037-1598454
DOI: 10.1055/s-0037-1598454
Posterbegehung – Sektion Pneumologische Onkologie
Lungenkarzinom II – Jens Kollmeier/Berlin, Andreas Gröschel/Aachen
Drug-induced myocarditis after nivolumab treatment in a patient with PDL-1-negative squamous cell carcinoma of the lung
Further Information
Publication History
Publication Date:
23 February 2017 (online)
Immunotherapy such as nivolumab is a new promising therapeutic option for advanced stage non small cell lung cancer (NSCLC). Due to the interference with the immune system previously unknown side effects are observed both in clinical studies and experience. Autoimmune phenomena effecting skin, gastrointestinal tract, endocrine glands, kidney and lung have been described. Up to now there is only limited information regarding potential cardiac side effects. We present a case of symptomatic drug induced myocarditis after nine cycles of nivolumab in a patient with efficient anticancer response.