Facial plast Surg 2017; 33(02): 233-240
DOI: 10.1055/s-0037-1598655
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Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Absorbable Implant to Treat Nasal Valve Collapse

Marion San Nicoló1, Klaus Stelter2, Haneen Sadick3, Murat Bas4, Alexander Berghaus1
  • 1Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilian University of Munich, Munich, Germany
  • 2HNO Zentrum Mangfall-Inn, Rosenheim, Germany
  • 3Division of Facial Plastic Surgery, Department of Otorhinolaryngology, University of Mannheim, Mannheim, Germany
  • 4Department of Otorhinolaryngology, Head and Neck Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany
Further Information

Publication History

Publication Date:
07 April 2017 (online)

Abstract

Objective To evaluate the safety and effectiveness of an absorbable implant for lateral cartilage support in subjects with nasal valve collapse (NVC) with 12 months follow-up.

Methods Thirty subjects with Nasal Obstruction Symptom Evaluation (NOSE) score ≥ 55 and isolated NVC were treated; 14 cases were performed in an operating suite under general anesthesia and 16 cases were performed in a clinic-based setting under local anesthesia. The implant, a polylactic acid copolymer, was placed with a delivery tool within the nasal wall to provide lateral cartilage support. Subjects were followed up through 12 months postprocedure.

Results Fifty-six implants were placed in 30 subjects. The mean preoperative NOSE score was 76.7 ± 14.8, with a range of 55 to 100. At 12 months, the mean score was 35.2 ± 29.2, reflecting an average within-patient reduction of –40.9 ± 31.2 points. The majority (76%) of the subjects were responders defined as having at least one NOSE class improvement or a NOSE score reduction of at least 20%. There were no adverse changes in cosmetic appearance at 12 months postprocedure. Three implants in three subjects required retrieval within 30 days postprocedure and resulted in no clinical sequelae.

Conclusion This study demonstrates safety and effectiveness of an absorbable implant for lateral cartilage support in subjects with NVC at 12 months postprocedure.