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Journal of Pediatric Neurology 2018; 16(03): 202-216
DOI: 10.1055/s-0037-1604478
Review Article
Georg Thieme Verlag KG Stuttgart · New York

Acute and Chronic Therapies in Pediatric Inflammatory Central Nervous System Diseases

Colin Wilbur
1   Division of Neurology, Department of Pediatrics, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada
,
E. Ann Yeh
1   Division of Neurology, Department of Pediatrics, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada
2   Department of Neurosciences and Mental Health, SickKids Research Institute, Toronto, Ontario, Canada
› Author Affiliations
Further Information

Publication History

30 June 2017

01 July 2017

Publication Date:
04 August 2017 (online)

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Abstract

Recognition of pediatric neuroinflammatory disorders has increased in recent years, together with an increased knowledge of the immune mechanisms underlying these disorders. These insights have led to paying greater attention to the classification of these disorders, and importantly, increasing information on therapeutic interventions that may improve outcomes. Furthermore, this has occurred in the wake of the development of multiple targeted immune therapies, thus creating a complex treatment landscape. This review aims to summarize the available literature regarding acute and chronic therapies for pediatric inflammatory central nervous system (CNS) disorders. A standardized approach to the initial management of these diseases is presented.

Keywords

neuroinflammatory disorders - autoimmune disorders - immune therapy

Supplementary Material

 

  • References

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