CC BY-NC-ND 4.0 · Joints 2017; 05(03): 191-194
DOI: 10.1055/s-0037-1605384
Technical Note
Georg Thieme Verlag KG Stuttgart · New York

Successful Treatment of Osgood–Schlatter Disease with Autologous-Conditioned Plasma in Two Patients

Dirk-Jonas Danneberg
1   Department of Orthopaedics and Sports Medicine, Darmstadt, Germany
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
24. August 2017 (online)

Abstract

Osgood–Schlatter Disease (OSD) is a painful, growth-related overuse condition of the tibial tuberosity, leading to inflammation of the patellar ligament at the tibial tuberosity. It primarily affects young adolescents, athletic population, and usually, resolves with age or skeletal maturity. Therapy is usually conservative, with surgery indicated in a minority of cases. For patients with treatment-resistant or refractory OSD, an alternative is the application of autologous platelet concentrate. Here, we describe two cases in which autologous-conditioned plasma therapy was used to treat OSD, and present the treatment protocol developed in our clinic.

Note

Patient consent has been obtained.


 
  • References

  • 1 Caine D, DiFiori J, Maffulli N. Physeal injuries in children's and youth sports: reasons for concern?. Br J Sports Med 2006; 40 (09) 749-760
  • 2 de Lucena GL, dos Santos Gomes C, Guerra RO. Prevalence and associated factors of Osgood-Schlatter syndrome in a population-based sample of Brazilian adolescents. Am J Sports Med 2011; 39 (02) 415-420
  • 3 Gholve PA, Scher DM, Khakharia S, Widmann RF, Green DW. Osgood Schlatter syndrome. Curr Opin Pediatr 2007; 19 (01) 44-50
  • 4 Gerulis V, Kalesinskas R, Pranckevicius S, Birgeris P. Importance of conservative treatment and physical load restriction to the course of Osgood-Schlatter's disease [in Lithuanian]. Medicina (Kaunas) 2004; 40 (04) 363-369
  • 5 Mital MA, Matza RA, Cohen J. The so-called unresolved Osgood-Schlatter lesion: a concept based on fifteen surgically treated lesions. J Bone Joint Surg Am 1980; 62 (05) 732-739
  • 6 Charousset C, Zaoui A, Bellaiche L, Bouyer B. Are multiple platelet-rich plasma injections useful for treatment of chronic patellar tendinopathy in athletes? a prospective study. Am J Sports Med 2014; 42 (04) 906-911
  • 7 Kon E, Filardo G, Delcogliano M. , et al. Platelet-rich plasma: new clinical application: a pilot study for treatment of jumper's knee. Injury 2009; 40 (06) 598-603
  • 8 Zayni R, Thaunat M, Fayard JM. , et al. Platelet-rich plasma as a treatment for chronic patellar tendinopathy: comparison of a single versus two consecutive injections. Muscles Ligaments Tendons J 2015; 5 (02) 92-98
  • 9 Foster TE, Puskas BL, Mandelbaum BR, Gerhardt MB, Rodeo SA. Platelet-rich plasma: from basic science to clinical applications. Am J Sports Med 2009; 37 (11) 2259-2272
  • 10 Lebiedziński R, Synder M, Buchcic P, Polguj M, Grzegorzewski A, Sibiński M. A randomized study of autologous conditioned plasma and steroid injections in the treatment of lateral epicondylitis. Int Orthop 2015; 39 (11) 2199-2203
  • 11 Laudy AB, Bakker EW, Rekers M, Moen MH. Efficacy of platelet-rich plasma injections in osteoarthritis of the knee: a systematic review and meta-analysis. Br J Sports Med 2015; 49 (10) 657-672
  • 12 Eppley BL, Woodell JE, Higgins J. Platelet quantification and growth factor analysis from platelet-rich plasma: implications for wound healing. Plast Reconstr Surg 2004; 114 (06) 1502-1508
  • 13 Andia I, Sánchez M, Maffulli Basic Science N. Molecular and biological aspects of platelet-rich plasma therapies. Oper Tech Orthop 2012; 22: 3-9
  • 14 Kon E, Filardo G, Di Martino A, Marcacci M. Platelet-rich plasma (PRP) to treat sports injuries: evidence to support its use. Knee Surg Sports Traumatol Arthrosc 2011; 19 (04) 516-527
  • 15 Boswell SG, Cole BJ, Sundman EA, Karas V, Fortier LA. Platelet-rich plasma: a milieu of bioactive factors. Arthroscopy 2012; 28 (03) 429-439
  • 16 Cerza F, Carnì S, Carcangiu A. , et al. Comparison between hyaluronic acid and platelet-rich plasma, intra-articular infiltration in the treatment of gonarthrosis. Am J Sports Med 2012; 40 (12) 2822-2827
  • 17 Carofino B, Chowaniec DM, McCarthy MB. , et al. Corticosteroids and local anesthetics decrease positive effects of platelet-rich plasma: an in vitro study on human tendon cells. Arthroscopy 2012; 28 (05) 711-719