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CC BY 4.0 · European J Pediatr Surg Rep. 2017; 05(01): e68-e70
DOI: 10.1055/s-0037-1607036
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Subcutaneous Panniculitis-Like T-Cell Lymphoma Presenting as a Local Inflammation of a Thigh in an 8-Month-Old Child

Kaja Gizewska-Kacprzak
1   Department of Pediatric and Oncological Surgery, Pomorski Uniwersytet Medyczny w Szczecinie, Szczecin, Poland
,
Katarzyna Karpinska-Kaczmarczyk
2   Department of Pathology, Pomorski Uniwersytet Medyczny w Szczecinie, Szczecin, Poland
,
Tomasz Ociepa
3   Department of Pediatrics, Hematology and Oncology, Pomorski Uniwersytet Medyczny w Szczecinie, Szczecin, Poland
› Author Affiliations
Further Information

Publication History

20 April 2017

25 July 2017

Publication Date:
28 October 2017 (online)

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Abstract

During infancy, skin inflammation is usually treated in basic pediatric care. In this study, we present a case of an 8-month-old girl with a 2-month history of an inflammation of the thigh treated locally by ointments and oral antibiotics in basic and dermatological care. The patient had a history of fever, sweating, and failure to thrive. The lactate dehydrogenase was elevated up to 869 U/L with low C-reactive protein (1.04 mg/L). Magnetic resonance imaging of the thigh reassured the diagnosis of local inflammation. Intravenous antibiotic caused mild local improvement, but the episodes of high fever sustained. The patient was transferred to our pediatric surgery department for treatment and surgical biopsy of the lesion. Histopathological examination confirmed a subcutaneous panniculitis-like T-cell lymphoma, which is a rare cytotoxic T-cell lymphoma representing less than 1% of non-Hodgkin lymphomas, uncommon in children. The patient was introduced to a chemotherapy protocol EURO-LB 2002 with good response. In a skin lesion that is associated with systemic symptoms and responding untypically to antibiotic treatment malignancy should be considered and biopsy not be postponed.

Keywords

cutaneous T-cell lymphoma - child - subcutaneous panniculitis-like T-cell lymphoma - immunohistochemistry
 

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