Abstract
Vascular access site complications can follow diagnostic coronary and peripheral angiography.
We compared the complication rates of the Catalyst vascular closure device, with the
complication rates after manual compression in patients undergoing diagnostic angiographic
procedures via femoral access. We studied 1,470 predominantly male patients undergoing
diagnostic coronary and peripheral angiography. Catalyst closure devices were used
in 436 (29.7%) patients and manual compression was used in 1,034 (70.3%) patients.
The former were allowed to ambulate after 2 hours, while the latter were allowed to
ambulate after 6 hours. Major complications occurred in 4 (0.9%) patients who had
a Catalyst device and in 14 (1.4%) patients who had manual compression (odds ratio
[OR]: 0.67, 95% confidence interval [CI]: 0.22–2.1, p = 0.49). Any complications occurred in 51 (11.7%) patients who had a Catalyst closure
device and in 64 (6.2%) patients who had manual compression (OR: 2, CI: 1.4–3, p < 0.01). After adjustment for other variables and for a propensity score reflecting
the probability to receive the closure device, the association of major complications
with the use of the closure device remained not significant (OR: 0.54, 95% CI: 0.17–1.7,
p = 0.29), while the association of any complications with the use of the Catalyst
device remained significant (OR: 1.9, 95% CI: 1.3–2.9, p < 0.01). The Catalyst device was not associated with an increased risk of major groin
complications but was associated with an increased risk of any complications compared
with manual compression. Patients receiving the closure device ambulated sooner.
Keywords
closure device - groin access complications - hematoma - bleeding
