Planta Medica International Open 2017; 4(S 01): S1-S202
DOI: 10.1055/s-0037-1608242
Poster Session
Georg Thieme Verlag KG Stuttgart · New York

Separation of 1'S-1'-acetoxychavicol acetate from a Alpinia galanga rhizome extract by fast centrifugal partition chromatography

P Sumthong Nakmee
1   Faculty of Science at Sriracha, Kasetsart University, Sriracha Campus, 199 Moo 6, Sukhumvit Road, Sriracha, 20230, Chonburi, Thailand
,
S Schwaiger
2   Institute of Pharmacy/Pharmacognosy, University of Innsbruck, CCB-Center for Chemistry and Biomedicine, Innrain 80 – 82/IV, 6020, Innsbruck, Austria
,
H Stuppner
2   Institute of Pharmacy/Pharmacognosy, University of Innsbruck, CCB-Center for Chemistry and Biomedicine, Innrain 80 – 82/IV, 6020, Innsbruck, Austria
› Author Affiliations
Further Information

Publication History

Publication Date:
24 October 2017 (online)

 

Fast Centrifugal Partition Chromatography (FCPC) is one of the modern techniques for separation of medicinal plants with multiple benefits. Alpinia galanga rhizome was used for seasoning and traditional medicine with various biological activities. The separation of a of Alpinia galanga rhizome hexane extract by an optimized water-free FCPC method enabled the successful isolation of 1'S-1,-acetoxychavicol acetate in a purity of > 93% and a yield of 76.47%. The compound inhibited the growth of the bacterium Bacillus thuringiensis and the fungus Beauveria bassiana pathogens causing the silkworm disease with MIC values of 62.5 and ≤2 µg/mL.