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Am J Perinatol 2018; 35(07): 643-647
DOI: 10.1055/s-0037-1608875
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Nasogastric Feeding Tubes May Not Contribute to Gastroesophageal Reflux in Preterm Infants

Swati V. Murthy
1   Department of Neonatology, Thomas Jefferson University, Nemours, Philadelphia, Pennsylvania
,
Apryle Funderburk
2   Pediatrix Medical Group, Columbia, South Carolina
,
Sheeja Abraham
3   Department of Pediatric Gastroenterology, Thomas Jefferson University, Nemours, Philadelphia, Pennsylvania
,
Michele Epstein
1   Department of Neonatology, Thomas Jefferson University, Nemours, Philadelphia, Pennsylvania
,
Joan DiPalma
3   Department of Pediatric Gastroenterology, Thomas Jefferson University, Nemours, Philadelphia, Pennsylvania
,
Zubair H. Aghai
1   Department of Neonatology, Thomas Jefferson University, Nemours, Philadelphia, Pennsylvania
› Institutsangaben Funding This study was supported by the Institutional Development Award (IDeA) (Aghai) from the National Institute of General Medical Sciences of the National Institutes of Health under grant number U54-GM104941 (PI: Binder-Macleod) and NIH COBRE P30GM114736 (PI: Thomas H. Shaffer).
Weitere Informationen

Publikationsverlauf

01. August 2017

21. Oktober 2017

Publikationsdatum:
30. November 2017 (online)

    Lizenzen und Reprints

Abstract

Objective The objective was to determine if the presence of a nasogastric (NG) feeding tube is associated with increased gastroesophageal reflux (GER) and acid exposure in preterm infants.

Study Design This is a retrospective study on preterm infants [gestational age (GA) <37 weeks] who were evaluated by multichannel intraluminal impedance and pH monitoring (MII-pH) between October 2009 and March 2016. Infants were divided into two groups, NG tube present and no feeding tube. GER events per hour and the percent of time with pH <4 during a 24-hour period were then compared.

Results Eighty-three infants were included, 41 had an NG tube present and 42 did not. The group without an NG tube had significantly more reflux events per hour (2.3 ± 2.9 vs. 1.3 ± 0.8, p < 0.05) even after adjusting for differences in birth weight, GA, corrected GA, and total fluid intake. There was no significant difference in acidic events per hour and acid exposure time between the two groups.

Conclusion The presence of a 5-French NG tube is not associated with an increase in GER or acid exposure in preterm infants. In fact, it appears that infants fed through an NG tube have fewer episodes of GER.

Keywords

multichannel intraluminal impedance - neonates - preterm infants - pH probe - gavage feeding
 

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