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CC BY-ND-NC 4.0 · Synthesis 2019; 51(05): 1037-1048
DOI: 10.1055/s-0037-1611637
DOI: 10.1055/s-0037-1611637
short review
Synthesis of Bullvalenes: Classical Approaches and Recent Developments
This work has been supported by Agencia Estatal de Investigación (CTQ2016-75960-P MINECO/AEI/FEDER, UE), AEI-Severo Ochoa Excellence Accreditation 2014-2018 (SEV-2013-0319), the MEC (FPU fellowship to S. F.), the European Research Council (Advanced Grant No. 321066), the AGAUR (2017 SGR 1257), the CERCA Program/Generalitat de Catalunya and the ICIQ Foundation.Further Information
Publication History
Received: 25 November 2018
Accepted: 28 November 2018
Publication Date:
14 January 2019 (online)
Dedicated to the memory of Prof. Félix Serratosa, a pioneer of organic synthesis in Spain
Published as part of the 50 Years SYNTHESIS – Golden Anniversary Issue
Abstract
The goal of this short review is to provide an overview of the different synthetic methodologies applied along the years for the synthesis of bullvalenes, prototypical fluxional molecules that were key in the understanding of valence tautomerism phenomena. Some interesting applications of these unique shapeshifting compounds are also presented.
1 Introduction
2 Classical Syntheses of Bullvalenes
3 Recent Developments in the Synthesis of Bullvalenes
4 Applications of Bullvalenes
5 Conclusion
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