Cerebral Vein Thrombosis not Related to Use of Oral Contraceptives in a 7-year-old Child Carrier of the Prothrombin 20210A Allele

Thromb Haemost 1999; 81(06): 991-992
DOI: 10.1055/s-0037-1614614

Letters to the Editor

Schattauer GmbH

Autoren

V. De Stefano

¹From the Department of Hematology, Catholic University, Rome, Italy
K. Paciaroni

¹From the Department of Hematology, Catholic University, Rome, Italy
P. Chiusolo

¹From the Department of Hematology, Catholic University, Rome, Italy
I. Casorelli

¹From the Department of Hematology, Catholic University, Rome, Italy
E. Rossi

¹From the Department of Hematology, Catholic University, Rome, Italy
L. Teofili

¹From the Department of Hematology, Catholic University, Rome, Italy
A. Di Mario

¹From the Department of Hematology, Catholic University, Rome, Italy
G. Leone

¹From the Department of Hematology, Catholic University, Rome, Italy

References
1 de Bruijn SFTM, Stam J, Koopman MMW, Vandenbroucke JP. for the Cerebral Venous Sinus Thrombosis Study Group. Case-control study of risk of cerebral sinus thrombosis in oral contraceptive users who are carriers of hereditary prothrombotic conditions. Br Med J 1998; 316:: 589-92.
2 Martinelli I, Sacchi E, Landi G, Taioli E, Duca F, Mannucci PM. High risk of cerebral vein thrombosis in carriers of a prothrombin-gene mutation and in users of oral contraceptives. N Engl J Med 1998; 338: 1793-7.
3 De Stefano V, Chiusolo P, Paciaroni K, Casorelli I, Rossi E, Molinari M, Servidei S, Tonali PA, Leone G. Prothrombin G20210A mutant genotype is a risk factor for cerebrovascular ischemic disease in young patients. Blood 1998; 91: 3562-5.
4 Teofili L, De Stefano V, Leone G, Micalizzi P, Iovino MS, Alfano G, Bizzi B. Haematological causes of venous thrombosis in young people: high incidence of myeloproliferative disorder as underlying disease in patients with splanchnic venous thrombosis. Thromb Haemost 1992; 67: 297-301.
5 Bloem BR, van Putten MJAM, van der Meer FJM, van Hilten JJ, Bertina RM. Superior sagittal sinus thrombosis in a patient heterozygous for the novel 20210A allele of the prothrombin gene. Thromb Haemost 1998; 79: 235.