Strong [68Ga]PSMA-HBED-CC accumulation in non-cancerous prostate tissue surrounding a PSMA-negative prostate carcinoma recurrence

Nuklearmedizin 2016; 55(05): N44-N45
DOI: 10.1055/s-0037-1616498

Case report

Schattauer GmbH

Strong [⁶⁸Ga]PSMA-HBED-CC accumulation in non-cancerous prostate tissue surrounding a PSMA-negative prostate carcinoma recurrence

Frederik A. Verburg

¹Department of Nuclear Medicine, RWTH University Hospital Aachen, Germany

²Department of Nuclear Medicine, Maastricht UMC, the Netherlands
Florian F. Behrendt

¹Department of Nuclear Medicine, RWTH University Hospital Aachen, Germany
Felix M. Mottaghy

¹Department of Nuclear Medicine, RWTH University Hospital Aachen, Germany

²Department of Nuclear Medicine, Maastricht UMC, the Netherlands
David Pfister

³Department of Urology, RWTH University Hospital Aachen, Germany
Florian Steib

⁴Department of Pathology, RWTH University Hospital Aachen, Germany
Ruth Knuechel

⁴Department of Pathology, RWTH University Hospital Aachen, Germany

References
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2 Bostwick DG, Pacelli A, Blute M. et al. Prostate specific membrane antigen expression in prostatic intraepithelial neoplasia and adenocarcinoma: a study of 184 cases. Cancer 1998; 82: 2256-2261.
3 Krohn T, Verburg FA, Pufe T. et al. [⁶⁸Ga]PSMA-HBED uptake mimicking lymph node metastasis in coeliac ganglia: an important pitfall in clinical practice. Eur J Nucl Med Mol Imaging 2015; 42: 210-214.
4 Silver DA, Pellicer I, Fair WR. et al. Prostate-specific membrane antigen expression in normal and malignant human tissues. Clin Cancer Res 1997; 3: 81-85.
5 Verburg FA, Pfister D, Heidenreich A. et al. Extent of disease in recurrent prostate cancer determined by [⁶⁸Ga]PSMA-HBED-CC PET/CT in relation to PSA levels, PSA doubling time and Gleason score. Eur J Nucl Med Mol Imaging. 2015 DOI